Rabbit RBMS1 Polyclonal Antibody | anti-RBMS1 antibody

RBMS1 Polyclonal Antibody

Cat. Num. AAA2529591

• Gene Names: RBMS1; YC1; MSSP; SCR2; HCC-4; MSSP-1; MSSP-2; MSSP-3; C2orf12
• Reactivity: Human, Mouse, Rat
• Applications: ELISA, Immunohistochemistry
• Purity: Antigen affinity purification
• Synonyms: RBMS1; Polyclonal Antibody; RBMS1 Polyclonal Antibody; YC1; MSSP; SCR2; HCC-4; MSSP-1; MSSP-2; MSSP-3; C2orf12; anti-RBMS1 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Antigen affinity purification
• Concentration: 0.9mg/mL (varies by lot)
• Sequence Length: 56

• Applicable Applications for anti-RBMS1 antibody: ELISA (EIA), Immunohistochemistry (IHC)
• Application Notes: IHC: 1:25-1:100
• Immunogen: Synthetic peptide of human RBMS1
• Buffer: PBS with 0.05% sodium azide, 50% glycerol, pH7.3
• Preparation and Storage: Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human colon cancer tissue using RBMS1 Polyclonal Antibody at dilution 1:30)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using RBMS1 Polyclonal Antibody at dilution 1:30)

Related Product Information for anti-RBMS1 antibody

his gene encodes a member of a small family of proteins which bind single stranded DNA/RNA. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and RNP2, originally described in RNA binding proteins, and required for DNA binding. These proteins have been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression and apoptosis. Several transcript variants, resulting from alternative splicing and encoding different isoforms, have been described. A pseudogene for this locus is found on chromosome 12.

NCBI and Uniprot Product Information

• NCBI GI #: 112180668
• NCBI GeneID: 5937
• Molecular Weight: 4,632 Da
• NCBI Official Full Name: RBMS1 protein
• NCBI Official Synonym Full Names: RNA binding motif, single stranded interacting protein 1
• NCBI Official Symbol: RBMS1
• NCBI Official Synonym Symbols: YC1; MSSP; SCR2; HCC-4; MSSP-1; MSSP-2; MSSP-3; C2orf12
• NCBI Protein Information: RNA-binding motif, single-stranded-interacting protein 1; c-myc gene single strand binding protein 2; cervical cancer oncogene 4; single-stranded DNA-binding protein MSSP-1; suppressor of CDC2 with RNA-binding motif 2; suppressor of cdc 2 (cdc13) with RNA binding motif 2
• UniProt Protein Name: RNA-binding motif, single-stranded-interacting protein 1
• Protein Family: RNA-binding motif, single-stranded-interacting protein
• UniProt Gene Name: RBMS1
• UniProt Synonym Gene Names: C2orf12; MSSP; MSSP1; SCR2
• UniProt Entry Name: RBMS1_HUMAN

NCBI Description

This gene encodes a member of a small family of proteins which bind single stranded DNA/RNA. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and RNP2, originally described in RNA binding proteins, and required for DNA binding. These proteins have been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression and apoptosis. Several transcript variants, resulting from alternative splicing and encoding different isoforms, have been described. A pseudogene for this locus is found on chromosome 12. [provided by RefSeq, Feb 2009]

Uniprot Description

RBMS1: Single-stranded DNA binding protein that interacts with the region upstream of the MYC gene. Binds specifically to the DNA sequence motif 5'-[AT]CT[AT][AT]T-3'. Probably has a role in DNA replication. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: RNA-binding; DNA replication

Chromosomal Location of Human Ortholog: 2q24.2

Cellular Component: nucleus

Molecular Function: protein binding; RNA binding; double-stranded DNA binding; nucleotide binding; single-stranded DNA binding

Biological Process: RNA processing; DNA replication