Goat anti-Human PTPRT Polyclonal Antibody | anti-PTPRT antibody

PTPRT, ID (Receptor-type Tyrosine-protein Phosphatase T, R-PTP-T, Receptor-type Tyrosine-protein Phosphatase Rho, RPTP-rho, KIAA0283)

Cat. Num. AAA6005239

• Reactivity: Human
• Applications: ELISA, Western Blot, Immunohistochemistry
• Purity: Affinity Purified; Purified by immunoaffinity chromatography.
• Synonyms: PTPRT; Polyclonal Antibody; ID (Receptor-type Tyrosine-protein Phosphatase T; R-PTP-T; Receptor-type Tyrosine-protein Phosphatase Rho; RPTP-rho; KIAA0283); Anti -PTPRT; anti-PTPRT antibody

• Host: Goat
• Reactivity: Human
• Clonality: Polyclonal
• Specificity: Recognizes human PTPRT. Species sequence homology: mouse
• Purity/Purification: Affinity Purified; Purified by immunoaffinity chromatography.
• Form/Format: Supplied as a liquid in TBS, pH 7.3, 0.5% BSA, 0.02% sodium azide.

• Applicable Applications for anti-PTPRT antibody: ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
• Application Notes: Suitable for use in ELISA, Western Blot and Immunohistochemistry.; Dilution: ELISA: 1:32,000; Western Blot: 0.3-1ug/ml; Immunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml
• Immunogen: Synthetic peptide corresponding to CNTWEKPMLDQAV from an internal region of human PTPRT.
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Immunohistochemistry (IHC)

(Human Brain, Cortex (formalin-fixed, paraffin-embedded) stained with PTPRT antibody at 5ug/ml followed by biotinylated goat IgG secondary antibody alkaline phosphatase-streptavidin and chromogen.)

Western Blot (WB)

(Antibody staining (0.3ug/ml) of Human Brain lysate (RIPA buffer, 35ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.)

Related Product Information for anti-PTPRT antibody

The protein is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP is a large protein that possesses a PTP domain at C-terminus, and multiple noncatalytic domains, which include a domain with similarity to band 4.1 superfamily of cytoskeletal-associated proteins, a region consisting of five PDZ domains, and a leucine zipper motif. This PTP was found to interact with, and dephosphorylate Fas receptor, as well as I-kappa B-alpha through the PDZ domains, which suggested its role in Fas mediated programmed cell death. This PTP was also shown to interact with GTPase-activating protein, and thus may function as a regulator of Rho signaling pathway. Four alternatively spliced transcript variants, which encode distinct proteins, have been reported.

Product Categories/Family for anti-PTPRT antibody

Antibodies; Abs to Enzymes; Phosphatase

NCBI and Uniprot Product Information

• NCBI GI #: 548491879
• NCBI GeneID: 102183250
• NCBI Accession #: XP_005688751.1
• NCBI GenBank Nucleotide #: XM_005688694.1
• NCBI Official Full Name: LOW QUALITY PROTEIN: receptor-type tyrosine-protein phosphatase T
• NCBI Official Symbol: PTPRT
• NCBI Protein Information: protein tyrosine phosphatase, receptor type, T
• Protein Family: Receptor-type tyrosine-protein phosphatase