Rabbit anti-Human PRDM12 Polyclonal Antibody | anti-PRDM12 antibody
PRDM12 Polyclonal Antibody
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a transcriptional regulator of sensory neuronal specification that plays a critical role in pain perception. The encoded protein contains an N-terminal PRDI-BF1 and RIZ homology (PR) domain, a SET domain, and three C-terminal C2H2 zinc finger DNA-binding domains. Naturally occurring mutations in this gene are associated with congenital insensitivity to pain (CIP), and hereditary sensory and autonomic neuropathies (HSAN's) affecting peripheral sensory and autonomic neurons. Deregulation of this gene is associated with solid cancers and hematological malignancies including chronic myeloid leukaemia. [provided by RefSeq, Mar 2017]
Uniprot Description
PRDM12: May be involved in transcriptional regulation.
Protein type: Methyltransferase, protein lysine, predicted; C2H2-type zinc finger protein
Chromosomal Location of Human Ortholog: 9q34.12
Cellular Component: nucleus
Molecular Function: methyltransferase activity; DNA binding; metal ion binding
Biological Process: methylation; neurogenesis; regulation of transcription, DNA-dependent; transcription, DNA-dependent
Disease: Neuropathy, Hereditary Sensory And Autonomic, Type Viii
Research Articles on PRDM12
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Product Notes
The PRDM12 prdm12 (Catalog #AAA8572323) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PRDM12 Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PRDM12 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the PRDM12 prdm12 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PRDM12, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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