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Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PHTF1 Polyclonal Antibody at dilution of 1:40(×200))

Rabbit anti-Human, Mouse PHTF1 Polyclonal Antibody | anti-PHTF1 antibody

PHTF1 Polyclonal Antibody

Gene Names
PHTF1; PHTF
Reactivity
Human, Mouse
Applications
Immunohistochemistry, ELISA
Purity
Antigen Affinity Purification
Synonyms
PHTF1; Polyclonal Antibody; PHTF1 Polyclonal Antibody; Phft; PHTF; Putative homeodomain transcription factor 1; anti-PHTF1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purification
Form/Format
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Concentration
0.66mg/mL (varies by lot)
Sequence Length
762
Applicable Applications for anti-PHTF1 antibody
Immunohistochemistry (IHC), ELISA (EIA)
Application Notes
IHC: 1:20-1:100
ELISA: 1:5000-1:10000
Immunogen
Fusion protein of human PHTF1
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PHTF1 Polyclonal Antibody at dilution of 1:40(×200))

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PHTF1 Polyclonal Antibody at dilution of 1:40(×200))
Related Product Information for anti-PHTF1 antibody
PHTF1 (putative homeodomain transcription factor 1), also known as PHTF, is a potential transcription regulator. It is a ubiquitously expressed integral, multipass membrane protein with predominant expression in testis. PHTF1 is associated with the ER (endoplasmic reticulum) and contains one bHLH (basic helix-loop-helix) domain. It is present in the cell during meiosis and spermiogenesis but, by the end of spermiogenesis, is released from the mature cell within the residual bodies. This implies that PHTF1 may play a role in the spermatozoa maturation process. In addition, PHTF1 is believed to interact with FEM1B and may be responsible for recruiting FEM1B to the surface of the ER membrane. This suggests that PHTF1 acts as a sequestering or anchoring protein for FEM1B. Two PHTF1 isoforms exist due to alternate splicing events. Isoform 2 is the shorter form and lacks the amino acid residues 648 to 762.
Product Categories/Family for anti-PHTF1 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
putative homeodomain transcription factor 1 isoform a
NCBI Official Synonym Full Names
putative homeodomain transcription factor 1
NCBI Official Symbol
PHTF1
NCBI Official Synonym Symbols
PHTF
NCBI Protein Information
putative homeodomain transcription factor 1
UniProt Protein Name
Putative homeodomain transcription factor 1
UniProt Gene Name
PHTF1
UniProt Synonym Gene Names
PHTF

Uniprot Description

PHTF1: May play a role in transcription regulation. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Transcription factor

Chromosomal Location of Human Ortholog: 1p13.2

Cellular Component: cis-Golgi network; endoplasmic reticulum; nucleus

Molecular Function: DNA binding; DNA binding transcription factor activity

Biological Process: regulation of transcription, DNA-templated; transcription, DNA-dependent

Research Articles on PHTF1

Similar Products

Product Notes

The PHTF1 phtf1 (Catalog #AAA2560742) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PHTF1 Polyclonal Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's PHTF1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), ELISA (EIA). IHC: 1:20-1:100 ELISA: 1:5000-1:10000. Researchers should empirically determine the suitability of the PHTF1 phtf1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PHTF1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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