Western Blot (WB)
(Host: RabbitTarget Name: RDBPSample Tissue: Human 293T Whole Cell lysatesAntibody Dilution: 1ug/ml)
Rabbit anti-Human NELFE Polyclonal Antibody | anti-NELFE antibody
NELFE Antibody - middle region
Western Blot (WB)
(Host: RabbitTarget Name: RDBPSample Tissue: Human 293T Whole Cell lysatesAntibody Dilution: 1ug/ml)
Western Blot (WB)
(Host: RabbitTarget Name: RDBPSample Tissue: Human 293T Whole Cell lysatesAntibody Dilution: 1ug/ml)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is part of a complex termed negative elongation factor (NELF) which represses RNA polymerase II transcript elongation. This protein bears similarity to nuclear RNA-binding proteins; however, it has not been demonstrated that this protein binds RNA. The protein contains a tract of alternating basic and acidic residues, largely arginine (R) and aspartic acid (D). The gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. [provided by RefSeq, Jul 2008]
Uniprot Description
RDBP: Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II. The NELF complex, which acts via an association with the DSIF complex and causes transcriptional pausing, is counteracted by the P-TEFb kinase complex. Belongs to the RRM NELF-E family.
Protein type: Transcription, coactivator/corepressor; Mitochondrial
Chromosomal Location of Human Ortholog: 6p21.3
Cellular Component: nucleoplasm; mitochondrion; nucleus
Molecular Function: protein binding; RNA binding; nucleotide binding
Biological Process: transcription from RNA polymerase II promoter; viral reproduction; positive regulation of viral transcription; RNA elongation from RNA polymerase II promoter; gene expression
Research Articles on NELFE
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Product Notes
The NELFE nelfe (Catalog #AAA3223505) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NELFE Antibody - middle region reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's NELFE can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the NELFE nelfe for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: FQRSISADDD LQESSRRPQR KSLYESFVSS SDRLRELGPD GEEAEGPGAG. It is sometimes possible for the material contained within the vial of "NELFE, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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