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Western Blot (WB) (Sample Data: Representative western blot with Anti-MEK2 (1:1000) using 20 ng of GST-tagged human recombinant MEK1 and MEK2.)

Rabbit MEK2 Polyclonal Antibody | anti-MEK2 antibody

Anti-MEK2

Reactivity
Western blot of human, mouse MEK2
MEK2 from other species may also be detectable.
Applications
Western Blot
Purity
Affinity chromatography
Synonyms
MEK2; Polyclonal Antibody; Anti-MEK2; anti-MEK2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Western blot of human, mouse MEK2
MEK2 from other species may also be detectable.
Clonality
Polyclonal
Isotype
Rabbit
Specificity
Recognizes the MEK2 protein
Purity/Purification
Affinity chromatography
Form/Format
PBS pH7.4, 0.02% sodium azide, 50% glycerol
Applicable Applications for anti-MEK2 antibody
Western Blot (WB)
Application Notes
WB: 21965:22964
Immunogen
Synthetic peptide corresponding to amino acids 392-396 of human MEK2
Preparation and Storage
Store at 4 degree C (add 0.1% NaN3) for several months, and at -20 degree C for longer periods. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For optimal performance, avoid repeated handling and multiple freeze/thaw cycles.

Western Blot (WB)

(Sample Data: Representative western blot with Anti-MEK2 (1:1000) using 20 ng of GST-tagged human recombinant MEK1 and MEK2.)

Western Blot (WB) (Sample Data: Representative western blot with Anti-MEK2 (1:1000) using 20 ng of GST-tagged human recombinant MEK1 and MEK2.)

Western Blot (WB)

(Sample Data: Representative western blot with Anti-MEK2 (1:1000) using 30 ug of HeLa, HEK-293T, Jurkat, and 3T6 cell lysate.)

Western Blot (WB) (Sample Data: Representative western blot with Anti-MEK2 (1:1000) using 30 ug of HeLa, HEK-293T, Jurkat, and 3T6 cell lysate.)
Related Product Information for anti-MEK2 antibody
MEK2 is the member of MAPK kinase (MAPKK) family of signaling protein kinases. MEK2 is a dual-specificity kinase that activates the extracellular signal-regulated kinase (ERK) and mitogen-activated protein (MAP) kinase upon agonist binding to receptors. MEK2 plays a key role in the Ras/Raf/MEK/ERK mitogen-activated protein kinase (MAPK) signaling pathways (1). Approximately 30% of all human cancers have a constitutively activated MAPK pathway, and constitutive activation of MEK2 results in cellular transformation. The ERK/MAP kinase cascade regulates cell growth and differentiation (2).
References
1. Shuichan, Xu et al: Differential Regulation of Mitogen-Activated Protein/ERK Kinase (MEK)1 and MEK2 and Activation by a Ras-Independent Mechanism. Mol. Endocrinol. 1997;11 (11): 1618-1625.
2. Louis-François, B, et al: Mek2 Is Dispensable for Mouse Growth and Development. Mol. Cellular Biol. 2003; 23 (14): 4778-4787.

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Product Notes

The MEK2 (Catalog #AAA516068) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-MEK2 reacts with Western blot of human, mouse MEK2 MEK2 from other species may also be detectable. and may cross-react with other species as described in the data sheet. AAA Biotech's MEK2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 21965:22964. Researchers should empirically determine the suitability of the MEK2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MEK2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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