Testing Data
(All lanes: Anti-CCL4, MBS175746Lane 1: Mouse Spleen Tissue LysateLane 2: Mouse Cardiac Muscle Tissue LysateLane 3: Mouse Lung Tissue LysateLane 4: Mouse Kidney Tissue LysateLane 5: Mouse Skeletal Muscle Tissue Lysate)
Rabbit anti-Mouse Macrophage Inflammatory Protein 1 beta Polyclonal Antibody | anti-CCL4 antibody
Anti-Macrophage Inflammatory Protein 1 beta antibody
Gene Names
Ccl4; Act-2; Mip1b; Scya4; MIP-1B; AT744.1
Reactivity
Mouse
Applications
Western Blot
Purity
Immunogen affinity purified.
Synonyms
Macrophage Inflammatory Protein 1 beta; Polyclonal Antibody; Anti-Macrophage Inflammatory Protein 1 beta antibody; C-C motif chemokine 4; chemokine(C-C motif) ligand 4; MIP 1 beta antibody; Secreted protein G 26 antibody; ACT 2 antibody; ACT-2 antibody; ACT2 antibody; AT744.1 antibody; AT744.2 antibody; C C motif chemokine 4 antibody; C C motif chemokine 4 like antibody; CC chemokine ligand 4 antibody; CC chemokine ligand 4L1d2 antibody; CC chemokine ligand 4L2 antibody; CCL4 antibody; CCL4_HUMAN antibody; ccl4l 1 antibody; CCL4L antibody; CCL4L1 antibody; Chemokine(C C motif) ligand 4 antibody; Chemokine(C C motif) ligand 4 like 1 antibody; Chemokine(C C motif) ligand 4 like 1; telomeric antibody; Chemokine(C C motif) ligand 4 like 2 antibody; Chemokine CC Motif Ligand 4 antibody; G 26 antibody; G 26 T lymphocyte secreted protein antibody; G-26 T-lymphocyte-secreted protein antibody; HC21 antibody; LAG 1 antibody; LAG-1 antibody; LAG1 antibody; Lymphocyte activation gene 1 antibody; Lymphocyte activation gene 1 protein antibody; Macrophage inflammatory protein 1 beta antibody; Macrophage inflammatory protein 1-beta antibody; Macrophage inflammatory protein 1b2 antibody; MGC104418 antibody; MGC126025 antibody; MGC126026 antibody; MIP-1-beta antibody; MIP-1-beta(1-69) antibody; MIP-1-beta(3-69) antibody; MIP1 beta antibody; MIP1B antibody; MIP1B1 antibody; Monocyte adherence induced protein 5 alpha antibody; PAT 744 antibody; Protein H400 antibody; SCYA2 antibody; SCYA4 antibody; SCYA4L antibody; Secreted protein G26 antibody; SIS gamma antibody; SIS-gamma antibody; Small inducible cytokine A4(homologous to mouse Mip 1b) antibody; Small inducible cytokine A4 antibody; Small-inducible cytokine A4 antibody; T cell activation protein 2 antibody; T-cell activation protein 2 antibody; anti-CCL4 antibody
Host
Rabbit
Reactivity
Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Immunogen affinity purified.
Form/Format
Lyophilized
Sequence Length
92
Applicable Applications for anti-CCL4 antibody
Western Blot (WB)
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of mouse Macrophage Inflammatory Protein 1 beta (74-88aa CANPSEPWVTEYMSD).
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
Testing Data
(All lanes: Anti-CCL4, MBS175746Lane 1: Mouse Spleen Tissue LysateLane 2: Mouse Cardiac Muscle Tissue LysateLane 3: Mouse Lung Tissue LysateLane 4: Mouse Kidney Tissue LysateLane 5: Mouse Skeletal Muscle Tissue Lysate)
Testing Data
(All lanes: Anti-CCL4, MBS175746Lane 1: Mouse Spleen Tissue LysateLane 2: Mouse Cardiac Muscle Tissue LysateLane 3: Mouse Lung Tissue LysateLane 4: Mouse Kidney Tissue LysateLane 5: Mouse Skeletal Muscle Tissue Lysate)
Related Product Information for anti-CCL4 antibody
Description: Rabbit IgG polyclonal antibody for C-C motif chemokine 4(CCL4) detection. Tested with WB in Mouse.
Background: Chemokine(C-C motif) ligand 4, also known as CCL4, is a protein which in humans is encoded by the CCL4 gene. It is a CC chemokine with specificity for CCR5 receptors. It is a chemoattractant for natural killer cells, monocytes and a variety of other immune cells. CCL4 is a major HIV-suppressive factor produced by CD8+ T cells. Performing-low memory CD8+ T cells that normally synthesize MIP-1-beta. Modi et al.(1991) assigned the SCYA4 gene to a slightly more distal location than had Irving et al.(1990): 17q21-q23 rather than 17q11-q21.
Background: Chemokine(C-C motif) ligand 4, also known as CCL4, is a protein which in humans is encoded by the CCL4 gene. It is a CC chemokine with specificity for CCR5 receptors. It is a chemoattractant for natural killer cells, monocytes and a variety of other immune cells. CCL4 is a major HIV-suppressive factor produced by CD8+ T cells. Performing-low memory CD8+ T cells that normally synthesize MIP-1-beta. Modi et al.(1991) assigned the SCYA4 gene to a slightly more distal location than had Irving et al.(1990): 17q21-q23 rather than 17q11-q21.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
10,168 Da
NCBI Official Full Name
C-C motif chemokine 4
NCBI Official Synonym Full Names
chemokine (C-C motif) ligand 4
NCBI Official Symbol
Ccl4
NCBI Official Synonym Symbols
Act-2; Mip1b; Scya4; MIP-1B; AT744.1
NCBI Protein Information
C-C motif chemokine 4; ACT2; SIS-gamma; MIP-1 beta; MIP-1-beta; immune activation protein 2; small inducible cytokine A4; small-inducible cytokine A4; macrophage inflammatory protein 1-beta
UniProt Protein Name
C-C motif chemokine 4
Protein Family
UniProt Gene Name
Ccl4
UniProt Synonym Gene Names
Mip1b; Scya4; ACT-2; ACT2; MIP-1-beta
UniProt Entry Name
CCL4_MOUSE
Uniprot Description
CCL4: Monokine with inflammatory and chemokinetic properties. Binds to CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form MIP-1-beta(3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5- mediated entry of HIV-1 in T-cells. MIP-1-beta(3-69) is also a ligand for CCR1 and CCR2 isoform B. Belongs to the intercrine beta (chemokine CC) family.
Protein type: Secreted; Chemokine; Motility/polarity/chemotaxis; Secreted, signal peptide
Cellular Component: extracellular space; extracellular region
Molecular Function: identical protein binding; protein binding; CCR1 chemokine receptor binding; chemokine activity; cytokine activity; CCR5 chemokine receptor binding
Biological Process: leukocyte chemotaxis; response to toxin; immune response; positive regulation of calcium-mediated signaling; positive regulation of tumor necrosis factor production; inflammatory response; chemotaxis; positive regulation of calcium ion transport; positive regulation of vascular permeability
Research Articles on CCL4
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Product Notes
The CCL4 ccl4 (Catalog #AAA175746) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-Macrophage Inflammatory Protein 1 beta antibody reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Macrophage Inflammatory Protein 1 beta can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the CCL4 ccl4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Macrophage Inflammatory Protein 1 beta, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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