Western Blot (WB)
(WB Suggested Anti-LAT2 AntibodyTitration: 1.0 ug/mlPositive Control: RPMI-8226 Whole CellLAT2 is supported by BioGPS gene expression data to be expressed in RPMI 8226)
Rabbit LAT2 Polyclonal Antibody | anti-LAT2 antibody
LAT2 antibody - C-terminal region
Western Blot (WB)
(WB Suggested Anti-LAT2 AntibodyTitration: 1.0 ug/mlPositive Control: RPMI-8226 Whole CellLAT2 is supported by BioGPS gene expression data to be expressed in RPMI 8226)
Western Blot (WB)
(WB Suggested Anti-LAT2 AntibodyTitration: 1.0 ug/mlPositive Control: RPMI-8226 Whole CellLAT2 is supported by BioGPS gene expression data to be expressed in RPMI 8226)
Target Description: This gene is one of the contiguous genes at 7q11.23 commonly deleted in Williams syndrome, a multisystem developmental disorder. This gene consists of at least 14 exons, and its alternative splicing generates 3 transcript variants, all encoding the same protein.
NCBI and Uniprot Product Information
NCBI Description
This gene is one of the contiguous genes at 7q11.23 commonly deleted in Williams syndrome, a multisystem developmental disorder. This gene consists of at least 14 exons, and its alternative splicing generates 3 transcript variants, all encoding the same protein. [provided by RefSeq, Jul 2008]
Uniprot Description
LAB: linker for activation of B cells (LAB) is an adaptor protein. B cell antigen receptor signaling leads to its phosphorylation and interaction with the adaptor protein Grb2. Decreased expression leads to a reduction in BCR-mediated calcium flux and Erk activation. Localized to lipid rafts.
Protein type: Adaptor/scaffold; Membrane protein, integral
Chromosomal Location of Human Ortholog: 7q11.23
Cellular Component: mast cell granule; integral to membrane; plasma membrane; lipid raft
Molecular Function: protein binding; SH2 domain binding
Biological Process: B cell receptor signaling pathway; B cell activation; calcium-mediated signaling; innate immune response; mast cell degranulation
Research Articles on LAT2
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Product Notes
The LAT2 lat2 (Catalog #AAA3216115) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The LAT2 antibody - C-terminal region reacts with Cow, Dog, Horse, Human, Mouse, Pig, Rabbit, Rat, Yeast and may cross-react with other species as described in the data sheet. AAA Biotech's LAT2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the LAT2 lat2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: KTGPTSGLCP SASPEEDEES EDYQNSASIH QWRESRKVMG QLQREASPGP. It is sometimes possible for the material contained within the vial of "LAT2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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