Rabbit KCNK7 Polyclonal Antibody | anti-KCNK7 antibody

KCNK7 Polyclonal Antibody

Cat. Num. AAA3007549

• Gene Names: KCNK7; TWIK3; K2p7.1
• Reactivity: Human, Mouse, Rat
• Applications: Western Blot
• Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
• Synonyms: KCNK7; Polyclonal Antibody; KCNK7 Polyclonal Antibody; Potassium channel subfamily K member 7; anti-KCNK7 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: KCNK7 polyclonal antibody detects endogenous levels of KCNK7 protein.
• Purity/Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
• Form/Format: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
• Sequence Length: 257

• Applicable Applications for anti-KCNK7 antibody: Western Blot (WB)
• Application Notes: WB: 1:500-1:1000
• Immunogen: Synthetic peptide, corresponding Human KCNK7.
• Preparation and Storage: Store at 4 degree C short term.; Aliquot and store at -20 degree C long term.; Avoid freeze-thaw cycles.

Western Blot (WB)

(Western Blot (WB) analysis of KCNK7 polyclonal antibody at 1:500 dilutionLane1:HCT116 whole cell lysate (40ug) Lane2:A549 whole cell lysate (40ug) Lane3:H9C2 whole cell lysate (40ug) Lane4:AML-12 whole cell lysate (40ug))

Related Product Information for anti-KCNK7 antibody

Potassium channel subfamily K member 7, Probable potassium channel subunit. No channel activity observed in vitro as protein remains in the endoplasmic reticulum. May need to associate with an as yet unknown partner in order to reach the plasma membrane.

NCBI and Uniprot Product Information

• NCBI GI #: 5031821
• NCBI GeneID: 10089
• NCBI Accession #: NP_005705.1
• NCBI GenBank Nucleotide #: NP_005705.1
• UniProt Accession #: Q9Y2U2
• Molecular Weight: ~ 31kDa
• NCBI Official Full Name: potassium channel subfamily K member 7 isoform C
• NCBI Official Synonym Full Names: potassium two pore domain channel subfamily K member 7
• NCBI Official Symbol: KCNK7
• NCBI Official Synonym Symbols: TWIK3; K2p7.1
• NCBI Protein Information: potassium channel subfamily K member 7
• UniProt Protein Name: Potassium channel subfamily K member 7
• Protein Family: Potassium channel subfamily
• UniProt Gene Name: KCNK7
• UniProt Entry Name: KCNK7_HUMAN

NCBI Description

This gene encodes a member of the superfamily of potassium channel proteins containing two pore-forming P domains. The product of this gene has not been shown to be a functional channel; however, it may require other non-pore-forming proteins for activity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

KCNK7: Probable potassium channel subunit. No channel activity observed in vitro as protein remains in the endoplasmic reticulum. May need to associate with an as yet unknown partner in order to reach the plasma membrane. Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 11q13

Cellular Component: integral to membrane; plasma membrane

Molecular Function: potassium channel activity; voltage-gated ion channel activity

Biological Process: synaptic transmission; potassium ion transport