Rabbit KCNG3 Polyclonal Antibody | anti-KCNG3 antibody

KCNG3 Polyclonal Antibody

Cat. Num. AAA3007591

• Gene Names: KCNG3; KV6.3; KV10.1
• Reactivity: Human, Mouse, Rat
• Applications: Western Blot
• Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
• Synonyms: KCNG3; Polyclonal Antibody; KCNG3 Polyclonal Antibody; Potassium voltage-gated channel subfamily G member 3; Voltage-gated potassium channel subunit Kv10.1; Voltage-gated potassium channel subunit Kv6.3; anti-KCNG3 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: KCNG3 polyclonal antibody detects endogenous levels of KCNG3 protein.
• Purity/Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
• Form/Format: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
• Sequence Length: 436

• Applicable Applications for anti-KCNG3 antibody: Western Blot (WB)
• Application Notes: WB: 1:500-1:1000
• Immunogen: Synthetic peptide, corresponding Human KCNG3.
• Preparation and Storage: Store at 4 degree C short term.; Aliquot and store at -20 degree C long term.; Avoid freeze-thaw cycles.

Western Blot (WB)

(Western Blot (WB) analysis of KCNG3 polyclonal antibody at 1:500 dilutionLane1:C6 whole cell lysate (40ug) Lane2:AML-12 whole cell lysate (40ug) Lane3:HCT116 whole cell lysate (40ug))

Related Product Information for anti-KCNG3 antibody

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily G. This member is a gamma subunit functioning as a modulatory molecule. Alternative splicing results in two transcript variants encoding distinct isoforms.

NCBI and Uniprot Product Information

• NCBI GI #: 19071574
• NCBI GeneID: 170850
• NCBI Accession #: NP_579875.1
• NCBI GenBank Nucleotide #: NP_579875.1
• UniProt Accession #: Q8TAE7
• Molecular Weight: ~ 50kDa
• NCBI Official Full Name: potassium voltage-gated channel subfamily G member 3 isoform 1
• NCBI Official Synonym Full Names: potassium voltage-gated channel modifier subfamily G member 3
• NCBI Official Symbol: KCNG3
• NCBI Official Synonym Symbols: KV6.3; KV10.1
• NCBI Protein Information: potassium voltage-gated channel subfamily G member 3
• UniProt Protein Name: Potassium voltage-gated channel subfamily G member 3
• Protein Family: Potassium voltage-gated channel subfamily
• UniProt Gene Name: KCNG3
• UniProt Entry Name: KCNG3_HUMAN

NCBI Description

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily G. This member is a gamma subunit functioning as a modulatory molecule. Alternative splicing results in two transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]

Uniprot Description

KCNG3: Potassium channel subunit. Modulates channel activity. Belongs to the potassium channel family. G (TC 1.A.1.2) subfamily. Kv6.3/KCNG3 sub-subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 2p21

Cellular Component: voltage-gated potassium channel complex; endoplasmic reticulum; integral to membrane; plasma membrane

Molecular Function: protein binding; delayed rectifier potassium channel activity

Biological Process: synaptic transmission; protein homooligomerization