Testing Data
Rabbit anti-Human, Rat K2P9.1 Polyclonal Antibody | anti-K2P9.1 antibody
Anti-K2P9.1 Antibody
Reactivity
Human, Rat
Applications
Western Blot
Purity
Affinity Purified On Immobilized Antigen.
Synonyms
K2P9.1; Polyclonal Antibody; Anti-K2P9.1 Antibody; K 2P9-1; anti-K2P9.1 antibody
Host
Rabbit
Reactivity
Human, Rat
Clonality
Polyclonal
Specificity
Human-15/17 residues identical.
Purity/Purification
Affinity Purified On Immobilized Antigen.
Form/Format
Liquid; PBS, pH 7.4 with 0.05% sodium azide.
Concentration
1ug/ul (varies by lot)
Applicable Applications for anti-K2P9.1 antibody
Western Blot (WB)
Application Notes
WB: Rat cerebellum lysate (1:200)
Immunogen
Peptide (C)DDYQQLELVILQSEPHR, corresponding to amino acid residues 57-73 of rat K2P9.1 (accession number Q923V6).
Preparation and Storage
This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use.
For extended storage, aliquot contents and freeze at-20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
For extended storage, aliquot contents and freeze at-20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Testing Data
Testing Data
Testing Data
Testing Data
Related Product Information for anti-K2P9.1 antibody
Acid-sensitive K+ channel 3, KCNK9, TASK3 K2P9.1 (also named TASK3 or KCNK9) is a member of the 2-pore (2P) domain K+ channels family that probably assemble as dimers to constitute a functional channel.1 These channels show little time or voltage dependence and are considered to be-leak-or-background-K+ channels, thereby generating background currents which help set the membrane resting potential and cell excitation. The channels are regulated by diverse physical and chemical stimuli including temperature, pH, mechanical stretch, inhalation anesthetics, etc.2 The physiological role of the K2P channels is not yet clear, though they were proposed to participate in breathing, aldosterone secretion and anesthetic-mediated neuronal activity. In human, expression of K2P9.1 is restricted in brain and its expression overlaps with the structurally related K2P3.1 (TASK1, KCNK3) channel. In rat, it is more widely expressed in other tissues as well as in brain. Unexpectedly, K2P9.1 was found to be over-expressed between 5 to 100-fold in 44% of breast cancer tumors tested. Transfection and over-expression of K2P9.1 in cell lines promotes tumor growth and confers resistance to hypoxia and serum deprivation.3 Recently, K2P9.1 was found to play an important role in K+-dependent apoptosis of cerebellar granules.4
Similar Products
Product Notes
The K2P9.1 (Catalog #AAA4159247) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-K2P9.1 Antibody reacts with Human, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's K2P9.1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: Rat cerebellum lysate (1:200). Researchers should empirically determine the suitability of the K2P9.1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "K2P9.1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
