Rabbit HA (Influenza A Virus Hemagglutinin) Polyclonal Antibody | anti-HA antibody

HA (Influenza A Virus Hemagglutinin) Antibody

Cat. Num. AAA840945

• Reactivity: Human, Mouse, Rat
• Applications: Western Blot
• Purity: Affinity purified
• Synonyms: HA (Influenza A Virus Hemagglutinin); Polyclonal Antibody; HA (Influenza A Virus Hemagglutinin) Antibody; anti-HA antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Affinity purified
• Form/Format: 100 ug (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.; Appearance: Colorless liquid
• Concentration: 0.5 mg/ml (varies by lot)
• Sequence Length: 320

• Applicable Applications for anti-HA antibody: Western Blot (WB)
• Application Notes: Western blotting (0.5-4 ug/ml). However, the optimal conditions should be determined individually. The antibody recognizes ~28 kDa HA in samples from human, mouse and rat origins. Reactivity to other species has not been tested.
• Immunogen: Synthetic peptide surrounding amino acid 100 of HA
• Handling: The antibody solution should be gently mixed before use.
• Preparation and Storage: At -20 degree C; Shelf Life: 12 months

Testing Data

Related Product Information for anti-HA antibody

Background: Influenza A viruses are surface glycoprotein, single stranded, segmented RNA viruses that are found in birds. Influenza A subtypes are based on the virus glycoproteins hemagglutinin(HA) and neuraminidase (NA). There are 16 different HA antigens and nine different N antigens for influenza A virus that have been isolated from wild birds.

NCBI and Uniprot Product Information

• NCBI GI #: 194593380
• Molecular Weight: 35,330 Da
• NCBI Official Full Name: hemagglutinin, partial
• UniProt Protein Name: Hemagglutinin
• Protein Family: Hemagglutinin
• UniProt Gene Name: HA
• UniProt Entry Name: B5AWZ3_9INFA

Uniprot Description

Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell. This attachment induces virion internalization of about two third of the virus particles through clathrin-dependent endocytosis and about one third through a clathrin- and caveolin-independent pathway. Plays a major role in the determination of host range restriction and virulence. Class I viral fusion protein. Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide. Several trimers are required to form a competent fusion pore.