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Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human colon cancer using MBS7046388 at dilution 1:100)

Rabbit anti-Human GALNT2 Polyclonal Antibody | anti-GALNT2 antibody

GALNT2 Antibody

Gene Names
GALNT2; GalNAc-T2
Reactivity
Human
Applications
ELISA, Immunohistochemistry
Purity
Antigen Affinity Purified
Synonyms
GALNT2; Polyclonal Antibody; GALNT2 Antibody; Polypeptide N-acetylgalactosaminyltransferase 2; Polypeptide GalNAc transferase 2; GalNAc-T2; pp-GaNTase 2; Protein-UDP acetylgalactosaminyltransferase 2; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 2; anti-GALNT2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purified
Form/Format
Liquid
Sequence Length
533
Applicable Applications for anti-GALNT2 antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes
Recommended dilution: IHC: 1:20-1:200
Species
Human
Immunogen
Recombinant human Polypeptide N-acetylgalactosaminyltransferase 2 protein (C-130AA)
Conjugate
Non-conjugated
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-68511
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human colon cancer using MBS7046388 at dilution 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human colon cancer using MBS7046388 at dilution 1:100)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human heart tissue using MBS7046388 at dilution 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human heart tissue using MBS7046388 at dilution 1:100)
Related Product Information for anti-GALNT2 antibody
Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Has a broad spectrum of substrates for peptides such as EA2, Muc5AC, Muc1a, Muc1b. Probably involved in O-linked glycosylation of the immunoglobulin A1 (IgA1) hinge region.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
30,256 Da
NCBI Official Full Name
polypeptide N-acetylgalactosaminyltransferase 2 isoform 2
NCBI Official Synonym Full Names
polypeptide N-acetylgalactosaminyltransferase 2
NCBI Official Symbol
GALNT2
NCBI Official Synonym Symbols
GalNAc-T2
NCBI Protein Information
polypeptide N-acetylgalactosaminyltransferase 2
UniProt Protein Name
Polypeptide N-acetylgalactosaminyltransferase 2
UniProt Gene Name
GALNT2
UniProt Synonym Gene Names
GalNAc-T2; pp-GaNTase 2
UniProt Entry Name
GALT2_HUMAN

NCBI Description

This gene encodes a member of the glycosyltransferase 2 protein family. Members of this family initiate mucin-type O-glycoslation of peptides in the Golgi apparatus. The encoded protein may be involved in O-linked glycosylation of the immunoglobulin A1 hinge region. This gene may influence triglyceride levels, and may be involved Type 2 diabetes, as well as several types of cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]

Uniprot Description

GALNT2: an enzyme that catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. A single-pass type II membrane protein that localizes to the Golgi apparatus membrane. Has a broad spectrum of substrates for peptides such as EA2, Muc5AC, Muc1a, Muc1b.

Protein type: Glycan Metabolism - O-glycan biosynthesis; Transferase; Membrane protein, integral; EC 2.4.1.41

Chromosomal Location of Human Ortholog: 1q41-q42

Cellular Component: endoplasmic reticulum membrane; Golgi apparatus; Golgi membrane; Golgi stack; membrane; perinuclear region of cytoplasm

Molecular Function: manganese ion binding; polypeptide N-acetylgalactosaminyltransferase activity; protein binding

Biological Process: immunoglobulin biosynthetic process; O-glycan processing; protein amino acid O-linked glycosylation; protein amino acid O-linked glycosylation via serine; protein amino acid O-linked glycosylation via threonine

Research Articles on GALNT2

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Product Notes

The GALNT2 galnt2 (Catalog #AAA7046388) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GALNT2 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's GALNT2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). Recommended dilution: IHC: 1:20-1:200. Researchers should empirically determine the suitability of the GALNT2 galnt2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GALNT2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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