Rabbit anti-Human FRMPD4 Polyclonal Antibody | anti-FRMPD4 antibody

FRMPD4, ID (FERM and PDZ Domain-containing Protein 4, PDZ Domain-containing Protein 10, PSD-95-interacting Regulator of Spine Morphogenesis, Preso, KIAA0316, PDZD10, PDZK10)

Cat. Num. AAA6002208

• Gene Names: FRMPD4; PDZD10; PDZK10
• Reactivity: Human
• Applications: ELISA, Western Blot, Immunohistochemistry
• Purity: Affinity Purified; Purified by immunoaffinity chromatography.
• Synonyms: FRMPD4; Polyclonal Antibody; ID (FERM and PDZ Domain-containing Protein 4; PDZ Domain-containing Protein 10; PSD-95-interacting Regulator of Spine Morphogenesis; Preso; KIAA0316; PDZD10; PDZK10); Anti -FRMPD4; anti-FRMPD4 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Specificity: Recognizes human FRMPD4.
• Purity/Purification: Affinity Purified; Purified by immunoaffinity chromatography.
• Form/Format: Supplied as a liquid in PBS, 0.02% sodium azide.

• Applicable Applications for anti-FRMPD4 antibody: ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
• Application Notes: Suitable for use in ELISA, Western Blot and Immunohistochemistry.; Dilution: Western Blot: 1-2ug/ml; Immunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml
• Immunogen: Synthetic peptide corresponding to 18aa from near the center of human FRMPD4.
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Immunohistochemistry (IHC)

(Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE))

Western Blot (WB)

(Western blot analysis of FRMPD4 in SK-N-SH cell lysate with FRMPD4 antibody at (A) 1 and (B) 2ug/ml.)

Related Product Information for anti-FRMPD4 antibody

Positive regulator of dendritic spine morphogenesis and density. Required for the maintenance of excitatory synaptic transmission. Binds phosphatidylinositol-4,5-bisphosphate.

Product Categories/Family for anti-FRMPD4 antibody

Antibodies; Abs to PDZ Domain

NCBI and Uniprot Product Information

• NCBI GI #: 219517980
• NCBI GeneID: 9758
• UniProt Accession #: Q14CM0; O15032; A8K0X9
• Molecular Weight: 144,379 Da
• NCBI Official Full Name: FRMPD4 protein
• NCBI Official Synonym Full Names: FERM and PDZ domain containing 4
• NCBI Official Symbol: FRMPD4
• NCBI Official Synonym Symbols: PDZD10; PDZK10
• NCBI Protein Information: FERM and PDZ domain-containing protein 4; Preso; PDZ domain containing 10; PDZ domain-containing protein 10; PSD-95-interacting FERM and PDZ domain protein; PSD-95-interacting regulator of spine morphogenesis
• UniProt Protein Name: FERM and PDZ domain-containing protein 4
• Protein Family: FERM and PDZ domain-containing protein
• UniProt Gene Name: FRMPD4
• UniProt Synonym Gene Names: KIAA0316; PDZD10; PDZK10; Preso
• UniProt Entry Name: FRPD4_HUMAN

NCBI Description

This gene encodes a multi-domain (WW, PDZ, FERM) containing protein. Through its interaction with other proteins (such as PSD-95), it functions as a positive regulator of dendritic spine morphogenesis and density, and is required for the maintenance of excitatory synaptic transmission. [provided by RefSeq, Jan 2010]

Uniprot Description

FRMPD4: Positive regulator of dendritic spine morphogenesis and density. Required for the maintenance of excitatory synaptic transmission. Binds phosphatidylinositol 4,5-bisphosphate.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: Xp22.2

Cellular Component: cytoskeleton; dendritic spine

Molecular Function: phosphatidylinositol-4,5-bisphosphate binding; protein binding

Biological Process: positive regulation of synapse structural plasticity