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Immunohistochemistry (IHC) (Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE))

Rabbit anti-Human FCAR / CD89 Polyclonal Antibody | anti-FCAR / CD89 antibody

Anti-FCAR / CD89 Antibody (aa57-84) IHC-plus

Gene Names
FCAR; CD89; FcalphaRI; CTB-61M7.2
Reactivity
Human
Applications
Immunohistochemistry, Western Blot
Purity
Immunoaffinity purified
Synonyms
FCAR / CD89; Polyclonal Antibody; Anti-FCAR / CD89 Antibody (aa57-84) IHC-plus; Rabbit Polyclonal to Human FCAR / CD89; Human FCAR / CD89; CD89 antigen; Fc alpha receptor; IgA Fc receptor; anti-FCAR / CD89 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
Human CD89
Purity/Purification
Immunoaffinity purified
Form/Format
PBS, 0.09% sodium azide
Sequence Length
287
Applicable Applications for anti-FCAR / CD89 antibody
Immunohistochemistry (IHC) Paraffin, Western Blot (WB)
Application Notes
IHC-P (1:100)
WB (1:1000)
Immunogen
FCAR / CD89 antibody was raised against kLH-conjugated synthetic peptide from internal region of human FCAR.
Immunogen Description
KLH-conjugated synthetic peptide from internal region of human FCAR.
Immunogen Type
Synthetic peptide
Antigen Modification
aa57-84
Target Species
Human
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months.
For long term storage store at -20 degree C.

Immunohistochemistry (IHC)

(Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE))

Immunohistochemistry (IHC) (Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE))

Immunohistochemistry (IHC)

(Human Lung: Formalin-Fixed, Paraffin-Embedded (FFPE))

Immunohistochemistry (IHC) (Human Lung: Formalin-Fixed, Paraffin-Embedded (FFPE))

Western Blot (WB)

(Western blot of FCAR (arrow) using rabbit polyclonal FCAR Antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the FCAR gene.)

Western Blot (WB) (Western blot of FCAR (arrow) using rabbit polyclonal FCAR Antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the FCAR gene.)
Related Product Information for anti-FCAR / CD89 antibody
FCAR Antibody, CD89 antigen Antibody, Fc alpha receptor Antibody, IgA Fc receptor Antibody, CD89 Antibody Description: FCAR / CD89 is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
28,343 Da
NCBI Official Full Name
immunoglobulin alpha Fc receptor isoform a
NCBI Official Synonym Full Names
Fc fragment of IgA receptor
NCBI Official Symbol
FCAR
NCBI Official Synonym Symbols
CD89; FcalphaRI; CTB-61M7.2
NCBI Protein Information
immunoglobulin alpha Fc receptor
UniProt Protein Name
Immunoglobulin alpha Fc receptor
UniProt Gene Name
FCAR
UniProt Synonym Gene Names
CD89; IgA Fc receptor
UniProt Entry Name
FCAR_HUMAN

NCBI Description

This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

FCAR: Binds to the Fc region of immunoglobulins alpha. Mediates several functions including cytokine production. 11 isoforms of the human protein are produced by alternative splicing.

Protein type: Immunoglobulin superfamily; Membrane protein, integral

Chromosomal Location of Human Ortholog: 19q13.42

Cellular Component: extracellular region; integral to plasma membrane; plasma membrane

Molecular Function: IgA binding

Biological Process: immune response

Research Articles on FCAR / CD89

Similar Products

Product Notes

The FCAR / CD89 fcar (Catalog #AAA2400455) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-FCAR / CD89 Antibody (aa57-84) IHC-plus reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's FCAR / CD89 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) Paraffin, Western Blot (WB). IHC-P (1:100) WB (1:1000). Researchers should empirically determine the suitability of the FCAR / CD89 fcar for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FCAR / CD89, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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