Western Blot (WB)
(Western blotAll lanes: ERLIN1 antibody at 4ug/ml+ Mouse brain tissueGoat polyclonal to rabbit at 1/10000 dilutionPredicted band size: 39 kDaObserved band size: 39 kDa)
Rabbit anti-Human, mouse ERLIN1 Polyclonal Antibody | anti-ERLIN1 antibody
ERLIN1 Antibody
Gene Names
ERLIN1; KE04; KEO4; SPFH1; SPG62; Erlin-1; C10orf69
Reactivity
Human, mouse
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Affinity Purified
Synonyms
ERLIN1; Polyclonal Antibody; ERLIN1 Antibody; Erlin-1; C10orf69; KE04; KEO4; SPFH1; Endoplasmic reticulum lipid raft-associated protein 1; Protein KE04; Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 1; SPFH domain-containing protein 1; anti-ERLIN1 antibody
Host
Rabbit
Reactivity
Human, mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity Purified
Form/Format
Liquid
Sequence Length
348
Applicable Applications for anti-ERLIN1 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
Recommended dilution: WB:1:500-2000, IHC:1:20-1:200
Immunogen
Recombinant human Erlin-1 protein
Conjugation
Non-conjugated
Storage Buffer
Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-244210 / sc-244211
Preparation and Storage
Shipped at 4 degree C. Upon delivery, aliquot and store at -20 degree C or -80 degree C.
Western Blot (WB)
(Western blotAll lanes: ERLIN1 antibody at 4ug/ml+ Mouse brain tissueGoat polyclonal to rabbit at 1/10000 dilutionPredicted band size: 39 kDaObserved band size: 39 kDa)
Western Blot (WB)
(Western blotAll lanes: ERLIN1 antibody at 4ug/ml+ Mouse brain tissueGoat polyclonal to rabbit at 1/10000 dilutionPredicted band size: 39 kDaObserved band size: 39 kDa)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human testis tissue using MBS7005231 at dilution of 1:100)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human testis tissue using MBS7005231 at dilution of 1:100)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human placenta tissue using MBS7005231 at dilution of 1:100)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human placenta tissue using MBS7005231 at dilution of 1:100)
Related Product Information for anti-ERLIN1 antibody
Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs). Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. Binds cholesterol and may promote ER retention of the SCAP-SREBF complex (PubMed:24217618).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
38,926 Da
NCBI Official Full Name
erlin-1
NCBI Official Synonym Full Names
ER lipid raft associated 1
NCBI Official Symbol
ERLIN1
NCBI Official Synonym Symbols
KE04; KEO4; SPFH1; SPG62; Erlin-1; C10orf69
NCBI Protein Information
erlin-1
UniProt Protein Name
Erlin-1
Protein Family
UniProt Gene Name
ERLIN1
UniProt Synonym Gene Names
C10orf69; KE04; KEO4; SPFH1; SPFH domain-containing protein 1
UniProt Entry Name
ERLN1_HUMAN
Uniprot Description
SPFH1: Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs). Belongs to the band 7/mec-2 family. Forms a heteromeric complex with ERLIN2.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 10q24.31
Cellular Component: endoplasmic reticulum; endoplasmic reticulum membrane; integral to membrane; protein complex
Molecular Function: cholesterol binding; protein binding
Biological Process: cholesterol metabolic process; ER-associated protein catabolic process; negative regulation of cholesterol biosynthetic process; negative regulation of fatty acid biosynthetic process; SREBP-mediated signaling pathway
Research Articles on ERLIN1
Similar Products
Product Notes
The ERLIN1 erlin1 (Catalog #AAA7005231) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ERLIN1 Antibody reacts with Human, mouse and may cross-react with other species as described in the data sheet. AAA Biotech's ERLIN1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). Recommended dilution: WB:1:500-2000, IHC:1:20-1:200. Researchers should empirically determine the suitability of the ERLIN1 erlin1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ERLIN1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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