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Immunohistochemistry (IHC)
(Immunochemical staining ECD in mouse colon with rabbit polyclonal antibody at 1:300 dilution, formalin-fixed paraffin embedded sections.)
Rabbit ECD Polyclonal Antibody | anti-ECD antibody
Anti-ECD Antibody, Rabbit Polyclonal
Gene Names
Ecd; Hsgt1; 5730461K03Rik
Reactivity
Mouse, Cynomolgus, HumanPredicted to React with: Pig (Species predicted to react based on 100% sequence homology)
Applications
Immunohistochemistry
Purity
Protein A & Antigen Affinity
Synonyms
ECD; Polyclonal Antibody; Anti-ECD Antibody; Rabbit Polyclonal; ECD/Ecdysoneless homolog Antibody; Rabbit PAb; Antigen Affinity Purified; ecdysoneless cell cycle regulator; Anti-5730461K03Rik Antibody; Anti-Hsgt1 Antibody; anti-ECD antibody
Host
Rabbit
Reactivity
Mouse, Cynomolgus, Human
Predicted to React with: Pig (Species predicted to react based on 100% sequence homology)
Predicted to React with: Pig (Species predicted to react based on 100% sequence homology)
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
Mouse ECD
Purity/Purification
Protein A & Antigen Affinity
Form/Format
Liquid; 0.2um filtered solution in PBS
Applicable Applications for anti-ECD antibody
Immunohistochemistry-Paraffin (IHC-P)
Application Notes
IHC-P: 1:200-1:1000
Immunogen
A synthetic peptide corresponding to the center region of the Mouse ECD/Ecdysoneless homolog
Conjugation
Unconjugated
Preparation
Produced in rabbits immunized with a synthetic peptide corresponding to the center region of the Mouse ECD/Ecdysoneless homolog, and purified by antigen affinity chromatography.
Preparation and Storage
This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Immunohistochemistry (IHC)
(Immunochemical staining ECD in mouse colon with rabbit polyclonal antibody at 1:300 dilution, formalin-fixed paraffin embedded sections.)
Immunohistochemistry (IHC)
(Immunochemical staining ECD in mouse colon with rabbit polyclonal antibody at 1:300 dilution, formalin-fixed paraffin embedded sections.)
Immunohistochemistry (IHC)
(Immunochemical staining ECD in mouse heart with rabbit polyclonal antibody at 1:300 dilution, formalin-fixed paraffin embedded sections.)
Immunohistochemistry (IHC)
(Immunochemical staining ECD in mouse heart with rabbit polyclonal antibody at 1:300 dilution, formalin-fixed paraffin embedded sections.)
Immunohistochemistry (IHC)
(Immunochemical staining ECD in human colon with rabbit polyclonal antibody at 1:300 dilution, formalin-fixed paraffin embedded sections.)
Immunohistochemistry (IHC)
(Immunochemical staining ECD in human colon with rabbit polyclonal antibody at 1:300 dilution, formalin-fixed paraffin embedded sections.)
Immunohistochemistry (IHC)
(Immunochemical staining ECD in cynomolgus heart with rabbit polyclonal antibody at 1:300 dilution, formalin-fixed paraffin embedded sections.)
Immunohistochemistry (IHC)
(Immunochemical staining ECD in cynomolgus heart with rabbit polyclonal antibody at 1:300 dilution, formalin-fixed paraffin embedded sections.)
Related Product Information for anti-ECD antibody
ECD, also known as ecdysoneless homolog, belongs to the SGT1 family. It is highly expressed in muscle and heart. ECD is a novel promoter of mammalian cell cycle progression. This function is related to its ability to remove the repressive effects of Rb-family tumor suppressors on E2F transcription factors. It is a novel tumor-promoting factor that is differentially expressed in pancreatic cancer and potentially regulates glucose metabolism within cancer cells. ECD may also be a transcriptional activator required for the expression of glycolytic genes.
References
Badzek S. et al., 2011, Wien Klin Wochenschr. 123 (23-24): 726-31.Zhao X. et al., 2012, Breast Cancer Res Treat. 134 (1): 171-80.Dey P. et al., 2012, Clin Cancer Res. 18 (22): 6188-98.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
71,710 Da
NCBI Official Full Name
protein SGT1 homolog
NCBI Official Synonym Full Names
ecdysoneless homolog (Drosophila)
NCBI Official Symbol
Ecd
NCBI Official Synonym Symbols
Hsgt1; 5730461K03Rik
NCBI Protein Information
protein SGT1 homolog; suppressor of S. cerevisiae gcr2
UniProt Protein Name
Protein SGT1 homolog
Protein Family
UniProt Gene Name
Ecd
UniProt Synonym Gene Names
Hsgt1; Sgt1
UniProt Entry Name
SGT1_MOUSE
Similar Products
Product Notes
The ECD ecd (Catalog #AAA8103495) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-ECD Antibody, Rabbit Polyclonal reacts with Mouse, Cynomolgus, Human Predicted to React with: Pig (Species predicted to react based on 100% sequence homology) and may cross-react with other species as described in the data sheet. AAA Biotech's ECD can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry-Paraffin (IHC-P). IHC-P: 1:200-1:1000. Researchers should empirically determine the suitability of the ECD ecd for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ECD, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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