Immunohistochemistry (IHC)
(Immunochemical staining of human TRPC7 in cynomolgus heart with rabbit polyclonal antibody at 1:300 dilution, formalin-fixed paraffin embedded sections.)
Rabbit TRPC7 Polyclonal Antibody | anti-TRPC7 antibody
Anti-TRPC7 Antibody, Rabbit Polyclonal
Gene Names
TRPC7; TRP7
Reactivity
HumanPredicted to React with: Mouse (Species predicted to react based on 100% sequence homology)
Applications
Immunohistochemistry
Purity
Protein A & Antigen Affinity
Synonyms
TRPC7; Polyclonal Antibody; Anti-TRPC7 Antibody; Rabbit Polyclonal; TRPC7 Antibody; Rabbit PAb; Antigen Affinity Purified; transient receptor potential cation channel; subfamily C; member 7; Anti-TRP7 Antibody; anti-TRPC7 antibody
Host
Rabbit
Reactivity
Human
Predicted to React with: Mouse (Species predicted to react based on 100% sequence homology)
Predicted to React with: Mouse (Species predicted to react based on 100% sequence homology)
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
Human TRPC7
Purity/Purification
Protein A & Antigen Affinity
Form/Format
Liquid; 0.2um filtered solution in PBS
Applicable Applications for anti-TRPC7 antibody
Immunohistochemistry-Paraffin (IHC-P)
Application Notes
IHC-P: 1:200-1:1000
Immunogen
A synthetic peptide corresponding to the center region of the Human TRPC7
Conjugation
Unconjugated
Preparation
Produced in rabbits immunized with a synthetic peptide corresponding to the center region of the Human TRPC7, and purified by antigen affinity chromatography.
Preparation and Storage
This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Immunohistochemistry (IHC)
(Immunochemical staining of human TRPC7 in cynomolgus heart with rabbit polyclonal antibody at 1:300 dilution, formalin-fixed paraffin embedded sections.)
Immunohistochemistry (IHC)
(Immunochemical staining of human TRPC7 in cynomolgus heart with rabbit polyclonal antibody at 1:300 dilution, formalin-fixed paraffin embedded sections.)
Related Product Information for anti-TRPC7 antibody
Canonical transient receptor potential7 (TRPC7) is the seventh identified member of the mammalian TRPC channel family, comprising nonselective cation channels activated through the phospholipase C (PLC) signaling pathway. TRPC7 localizes in the surface and tubular sarcolemma of cardiomyocytes in normal adult rats and its expression significantly decreases in hypertrophied cardiomyocytes from renovascular hypertensive rats. TRPC7 may thus play a significant role in normal physiological settings in the heart. the expression characteristics of transient receptor potential canonical 7 (TRPC7) in normal and hypertrophic cardiac myocytes.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
92,429 Da
NCBI Official Full Name
short transient receptor potential channel 7 isoform 3
NCBI Official Synonym Full Names
transient receptor potential cation channel subfamily C member 7
NCBI Official Symbol
TRPC7
NCBI Official Synonym Symbols
TRP7
NCBI Protein Information
short transient receptor potential channel 7
UniProt Protein Name
Short transient receptor potential channel 7
Protein Family
UniProt Gene Name
TRPC7
UniProt Synonym Gene Names
TRP7; TrpC7; TRP-7; hTRP7
UniProt Entry Name
TRPC7_HUMAN
Uniprot Description
TRPC7: Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG). May also be activated by intracellular calcium store depletion. Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily. TRPC7 sub-subfamily. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Channel, calcium; Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 5q31.1
Cellular Component: cis-Golgi network; integral to plasma membrane; nuclear envelope; perinuclear region of cytoplasm; plasma membrane
Molecular Function: calcium channel activity; protein binding; store-operated calcium channel activity
Biological Process: cytosolic calcium ion homeostasis; manganese ion transport; platelet activation; single fertilization
Research Articles on TRPC7
Similar Products
Product Notes
The TRPC7 trpc7 (Catalog #AAA8103720) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-TRPC7 Antibody, Rabbit Polyclonal reacts with Human Predicted to React with: Mouse (Species predicted to react based on 100% sequence homology) and may cross-react with other species as described in the data sheet. AAA Biotech's TRPC7 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry-Paraffin (IHC-P). IHC-P: 1:200-1:1000. Researchers should empirically determine the suitability of the TRPC7 trpc7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TRPC7, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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