Immunohistochemistry (IHC)
(Immunochemical staining FXR1 in human skin with rabbit polyclonal antibody (1:1000, formalin-fixed paraffin embedded sections).)
Rabbit FXR1 Polyclonal Antibody | anti-FXR1 antibody
Anti-FXR1 Antibody, Rabbit Polyclonal
Gene Names
FXR1; FXR1P
Reactivity
Human, MousePredicted to React with: Rat (Species predicted to react based on 100% sequence homology)
Applications
Immunohistochemistry
Purity
Protein A & Antigen Affinity
Synonyms
FXR1; Polyclonal Antibody; Anti-FXR1 Antibody; Rabbit Polyclonal; FXR1 Antibody; Rabbit PAb; Antigen Affinity Purified; fragile X mental retardation; autosomal homolog 1; Anti-FXR1P Antibody; anti-FXR1 antibody
Host
Rabbit
Reactivity
Human, Mouse
Predicted to React with: Rat (Species predicted to react based on 100% sequence homology)
Predicted to React with: Rat (Species predicted to react based on 100% sequence homology)
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
Human FXR1
Purity/Purification
Protein A & Antigen Affinity
Form/Format
Liquid; 0.2um filtered solution in PBS
Applicable Applications for anti-FXR1 antibody
Immunohistochemistry-Paraffin (IHC-P)
Application Notes
IHC-P: 1:500-1:2000
Immunogen
A synthetic peptide corresponding to the center region of the Human FXR1
Conjugation
Unconjugated
Preparation
Produced in rabbits immunized with a synthetic peptide corresponding to the center region of the Human FXR1, and purified by antigen affinity chromatography.
Preparation and Storage
This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Immunohistochemistry (IHC)
(Immunochemical staining FXR1 in human skin with rabbit polyclonal antibody (1:1000, formalin-fixed paraffin embedded sections).)
Immunohistochemistry (IHC)
(Immunochemical staining FXR1 in human skin with rabbit polyclonal antibody (1:1000, formalin-fixed paraffin embedded sections).)
Immunohistochemistry (IHC)
(Immunochemical staining FXR1 in mouse skin with rabbit polyclonal antibody (1:1000, formalin-fixed paraffin embedded sections).)
Immunohistochemistry (IHC)
(Immunochemical staining FXR1 in mouse skin with rabbit polyclonal antibody (1:1000, formalin-fixed paraffin embedded sections).)
Related Product Information for anti-FXR1 antibody
Fragile X mental retardation-related protein 1 (FXR1) is a cytoplasmic RNA-binding protein highly conserved among vertebrates. It has been studied for its role in muscle development, inflammation, and tumorigenesis, being related, for example, to metastasizing behavior in human and canine uveal melanoma. FXR1 is a novel COX-2 regulatory factor. FXR1 was highly expressed in human placental villi during early pregnancy. FXR1 is a multifunctional protein involved in translational regulation and stabilization of its mRNA targets in heart muscle, it directly regulates major gap junction components, contributing to proper cell-cell communication in the heart. FXR1-regulated senescence is irreversible and FXR1-depleted cells fail to form colonies to re-enter cellular proliferation. FXR1 expression is a candidate biomarker predictive of poor survival in multiple solid tumors including nonsmall cell lung cancer (NSCLC).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
59,920 Da
NCBI Official Full Name
fragile X mental retardation syndrome-related protein 1 isoform b
NCBI Official Synonym Full Names
fragile X mental retardation, autosomal homolog 1
NCBI Official Symbol
FXR1
NCBI Official Synonym Symbols
FXR1P
NCBI Protein Information
fragile X mental retardation syndrome-related protein 1; hFXR1p
UniProt Protein Name
Fragile X mental retardation syndrome-related protein 1
Protein Family
UniProt Gene Name
FXR1
UniProt Synonym Gene Names
hFXR1p
UniProt Entry Name
FXR1_HUMAN
Similar Products
Product Notes
The FXR1 fxr1 (Catalog #AAA8100799) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-FXR1 Antibody, Rabbit Polyclonal reacts with Human, Mouse Predicted to React with: Rat (Species predicted to react based on 100% sequence homology) and may cross-react with other species as described in the data sheet. AAA Biotech's FXR1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry-Paraffin (IHC-P). IHC-P: 1:500-1:2000. Researchers should empirically determine the suitability of the FXR1 fxr1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FXR1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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