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Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human testis tissue using MBS7045781 at dilution 1:100)

Rabbit anti-Human DSTYK Polyclonal Antibody | anti-DSTYK antibody

DSTYK Antibody

Gene Names
DSTYK; RIP5; RIPK5; CAKUT1; DustyPK; HDCMD38P
Reactivity
Human
Applications
ELISA, Immunohistochemistry
Purity
Antigen Affinity Purified
Synonyms
DSTYK; Polyclonal Antibody; DSTYK Antibody; Dual serine/threonine and tyrosine protein kinase; Dusty protein kinase; Dusty PK; RIP-homologous kinase; Receptor-interacting serine/threonine-protein kinase 5; Sugen kinase 496; SgK496; KIAA0472; RIP5; RIPK5; SGK496; HDCMD38P; anti-DSTYK antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purified
Form/Format
Liquid
Sequence Length
929
Applicable Applications for anti-DSTYK antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes
Recommended dilution: IHC: 1:20-1:200
Species
Human
Immunogen
Recombinant human Dual serine/threonine and tyrosine protein kinase protein (C-250AA)
Conjugate
Non-conjugated
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-162107 / sc-162109 / sc-162110 / sc-135373
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human testis tissue using MBS7045781 at dilution 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human testis tissue using MBS7045781 at dilution 1:100)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using MBS7045781 at dilution 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using MBS7045781 at dilution 1:100)
Related Product Information for anti-DSTYK antibody
Acts as a positive regulator of ERK phosphorylation downstream of fibroblast growth factor-receptor activation. May induce both caspase-dependent apoptosis and caspase-independent cell death.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
20,769 Da
NCBI Official Full Name
dual serine/threonine and tyrosine protein kinase isoform 1
NCBI Official Synonym Full Names
dual serine/threonine and tyrosine protein kinase
NCBI Official Symbol
DSTYK
NCBI Official Synonym Symbols
RIP5; RIPK5; CAKUT1; DustyPK; HDCMD38P
NCBI Protein Information
dual serine/threonine and tyrosine protein kinase
UniProt Protein Name
Dual serine/threonine and tyrosine protein kinase
UniProt Gene Name
DSTYK
UniProt Synonym Gene Names
KIAA0472; RIP5; RIPK5; SGK496; Dusty PK; SgK496
UniProt Entry Name
DUSTY_HUMAN

NCBI Description

This gene encodes a dual serine/threonine and tyrosine protein kinase which is expressed in multiple tissues. It is thought to function as a regulator of cell death. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]

Uniprot Description

DSTYK: a serine/threonine protein kinase of the 'Other-Unique' family, most closely related to kinases of the TKL family including IRAK and RIPK. Overexpression induces apoptotic cell death. The caspase inhibitor crmA apparently blocks DNA fragmentation but not apoptosis, suggesting that SgK496 may induce both caspase-dependent apoptosis and caspase-independent cell death. Four alternatively spliced isoforms have been described.

Protein type: Kinase, protein; Protein kinase, Other; EC 2.7.12.1; Protein kinase, Ser/Thr (non-receptor); Motility/polarity/chemotaxis; Other group; Other-Unique family

Chromosomal Location of Human Ortholog: 1q32.1

Cellular Component: apical plasma membrane; basolateral plasma membrane; cytoplasm; cytosol

Molecular Function: protein serine/threonine kinase activity

Biological Process: positive regulation of fibroblast growth factor receptor signaling pathway; positive regulation of kinase activity

Disease: Congenital Anomalies Of Kidney And Urinary Tract, Susceptibility To

Research Articles on DSTYK

Similar Products

Product Notes

The DSTYK dstyk (Catalog #AAA7045781) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The DSTYK Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's DSTYK can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). Recommended dilution: IHC: 1:20-1:200. Researchers should empirically determine the suitability of the DSTYK dstyk for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DSTYK, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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