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Western Blot (WB) (Gel: 6%SDS-PAGE Lysate: 40 μ g Lane 1-2: 823 cells, hepg2 cells Primary antibody: 1/200 dilution Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 1 minute)

Rabbit anti-Human DSTYK Polyclonal Antibody | anti-DSTYK antibody

DSTYK Antibody

Gene Names
DSTYK; RIP5; RIPK5; CAKUT1; DustyPK; HDCMD38P
Reactivity
Human
Applications
Western Blot, Immunohistochemistry
Purity
Antigen Affinity Purification
Synonyms
DSTYK; Polyclonal Antibody; DSTYK Antibody; RIP5; RIPK5; CAKUT1; DustyPK; HDCMD38P; anti-DSTYK antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total DSTYK protein.
Purity/Purification
Antigen Affinity Purification
Form/Format
Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
Concentration
1.3 mg/ml (varies by lot)
Sequence Length
929
Applicable Applications for anti-DSTYK antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
Western Blot: 1:200-1:1000
Immunohistochemistry: 1:10-1:50
Immunogen
Fusion protein of human DSTYK
Immunogen Type
Protein
Preparation and Storage
Store at -20 degree C

Western Blot (WB)

(Gel: 6%SDS-PAGE Lysate: 40 μ g Lane 1-2: 823 cells, hepg2 cells Primary antibody: 1/200 dilution Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 1 minute)

Western Blot (WB) (Gel: 6%SDS-PAGE Lysate: 40 μ g Lane 1-2: 823 cells, hepg2 cells Primary antibody: 1/200 dilution Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 1 minute)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue using at dilution 1/25,)

Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue using at dilution 1/25,)
Related Product Information for anti-DSTYK antibody
This gene encodes a dual serine/threonine and tyrosine protein kinase which is expressed in multiple tissues. It is thought to function as a regulator of cell death. Multiple transcript variants encoding different isoformshave been found for this gene.
Product Categories/Family for anti-DSTYK antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
20,769 Da
NCBI Official Full Name
dual serine/threonine and tyrosine protein kinase isoform 1
NCBI Official Synonym Full Names
dual serine/threonine and tyrosine protein kinase
NCBI Official Symbol
DSTYK
NCBI Official Synonym Symbols
RIP5; RIPK5; CAKUT1; DustyPK; HDCMD38P
NCBI Protein Information
dual serine/threonine and tyrosine protein kinase
UniProt Protein Name
Dual serine/threonine and tyrosine protein kinase
UniProt Gene Name
DSTYK
UniProt Synonym Gene Names
KIAA0472; RIP5; RIPK5; SGK496; Dusty PK; SgK496
UniProt Entry Name
DUSTY_HUMAN

Uniprot Description

DSTYK: a serine/threonine protein kinase of the 'Other-Unique' family, most closely related to kinases of the TKL family including IRAK and RIPK. Overexpression induces apoptotic cell death. The caspase inhibitor crmA apparently blocks DNA fragmentation but not apoptosis, suggesting that SgK496 may induce both caspase-dependent apoptosis and caspase-independent cell death. Four alternatively spliced isoforms have been described.

Protein type: EC 2.7.12.1; Kinase, protein; Motility/polarity/chemotaxis; Other group; Other-Unique family; Protein kinase, Other; Protein kinase, Ser/Thr (non-receptor)

Chromosomal Location of Human Ortholog: 1q32.1

Cellular Component: apical plasma membrane; basolateral plasma membrane; cytoplasm; cytosol

Molecular Function: protein serine/threonine kinase activity

Biological Process: positive regulation of fibroblast growth factor receptor signaling pathway; positive regulation of kinase activity

Disease: Congenital Anomalies Of Kidney And Urinary Tract, Susceptibility To

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Product Notes

The DSTYK dstyk (Catalog #AAA9415543) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The DSTYK Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's DSTYK can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). Western Blot: 1:200-1:1000 Immunohistochemistry: 1:10-1:50. Researchers should empirically determine the suitability of the DSTYK dstyk for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DSTYK, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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