Western Blot (WB)
(WB Suggested Anti-DGKH Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:12500Positive Control: Human Liver)
Rabbit DGKH Polyclonal Antibody | anti-DGKH antibody
DGKH antibody - middle region
Western Blot (WB)
(WB Suggested Anti-DGKH Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:12500Positive Control: Human Liver)
Western Blot (WB)
(WB Suggested Anti-DGKH Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:12500Positive Control: Human Liver)
Target Description: DGKH is a member of the diacylglycerol kinase (DGK) enzyme family of proteins, specifically the type II DGK subfamily. Members of this family are involved in regulating the intracellular concentrations of diacylglycerol and phosphatidic acid. This gene encodes a member of the diacylglycerol kinase (DGK) enzyme family of proteins, specifically the type II DGK subfamily. Members of this family are involved in regulating the intracellular concentrations of diacylglycerol and phosphatidic acid. Two transcript variants encoding distinct isoforms have been identified for this gene.
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the diacylglycerol kinase (DGK) enzyme family. Members of this family are involved in regulating intracellular concentrations of diacylglycerol and phosphatidic acid. Variation in this gene has been associated with bipolar disorder. Alternatively spliced transcript variants have been identified. [provided by RefSeq, Jul 2014]
Uniprot Description
DGKH: Phosphorylates diacylglycerol (DAG) to generate phosphatidic acid (PA). Plays a key role in promoting cell growth. Activates the Ras/B-Raf/C-Raf/MEK/ERK signaling pathway induced by EGF. Regulates the recruitment of RAF1 and BRAF from cytoplasm to membranes and their heterodimerization. Belongs to the eukaryotic diacylglycerol kinase family. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Lipid Metabolism - glycerolipid; Motility/polarity/chemotaxis; Kinase, other; EC 2.7.1.107; Lipid Metabolism - glycerophospholipid
Chromosomal Location of Human Ortholog: 13q14.11
Cellular Component: nuclear membrane; cytoplasm; plasma membrane; nucleus; endosome
Molecular Function: metal ion binding; diacylglycerol kinase activity; ATP binding; NAD+ kinase activity
Biological Process: platelet activation; protein kinase C activation; blood coagulation; phosphorylation; protein oligomerization
Research Articles on DGKH
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Product Notes
The DGKH dgkh (Catalog #AAA3207896) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The DGKH antibody - middle region reacts with Dog, Horse, Human and may cross-react with other species as described in the data sheet. AAA Biotech's DGKH can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the DGKH dgkh for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: EPANQSSDYD STETDESKEE AKDDGAKESI TVKTAPRSPD ARASYGHSQT. It is sometimes possible for the material contained within the vial of "DGKH, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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