Immunohistochemistry - Paraffin (IHC)
(Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE))
Rabbit CHRNA10 Polyclonal Antibody | anti-CHRNA10 antibody
Anti-CHRNA10 Antibody (aa179-206) IHC-plus
Predicted Reactivity: Rat (at least 90% immunogen sequence identity)
Predicted Reactivity: Rat (at least 90% immunogen sequence identity)
WB (1:1000)
For long term storage store at -20 degree C.
Immunohistochemistry - Paraffin (IHC)
(Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE))
Immunohistochemistry - Paraffin (IHC)
(Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE))
Immunohistochemistry - Paraffin (IHC)
(Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE))
Immunohistochemistry - Paraffin (IHC)
(Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE))
Western Blot (WB)
(CHRNA10 Antibody western blot of NCI-H292,MDA-MB453,ZR-75-1 cell line lysates (35 ug/lane). The CHRNA10 antibody detected the CHRNA10 protein (arrow).)
Western Blot (WB)
(CHRNA10 Antibody western blot of NCI-H292,MDA-MB453,ZR-75-1 cell line lysates (35 ug/lane). The CHRNA10 antibody detected the CHRNA10 protein (arrow).)
NCBI and Uniprot Product Information
Uniprot Description
nAChRA10: Ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding may induce an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane. In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and reducing the range of dynamic hearing. This may protect against acoustic trauma. Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. Alpha- 10/CHRNA10 sub-subfamily.
Protein type: Channel, cation; Channel, ligand-gated; Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 11p15.5
Cellular Component: membrane; nicotinic acetylcholine-gated receptor-channel complex
Molecular Function: acetylcholine binding; acetylcholine receptor activity; nicotinic acetylcholine-activated cation-selective channel activity; receptor binding
Biological Process: elevation of cytosolic calcium ion concentration; regulation of cell proliferation; synaptic transmission, cholinergic
Research Articles on CHRNA10
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Product Notes
The CHRNA10 chrna10 (Catalog #AAA2400305) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-CHRNA10 Antibody (aa179-206) IHC-plus reacts with Human Predicted Reactivity: Rat (at least 90% immunogen sequence identity) and may cross-react with other species as described in the data sheet. AAA Biotech's CHRNA10 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) Paraffin, Western Blot (WB). IHC-P (1:10 - 1:100) WB (1:1000). Researchers should empirically determine the suitability of the CHRNA10 chrna10 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CHRNA10, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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