Rabbit anti-Human, Mouse CHD1 Polyclonal Antibody | anti-CHD1 antibody

Anti-CHD1 Antibody, Rabbit Polyclonal

Cat. Num. AAA8101085

• Gene Names: Chd1; AI851787; AW555109; 4930525N21Rik
• Reactivity: Human, Mouse
• Applications: Immunohistochemistry
• Purity: Protein A & Antigen Affinity
• Synonyms: CHD1; Polyclonal Antibody; Anti-CHD1 Antibody; Rabbit Polyclonal; CHD1 Antibody; Rabbit PAb; Antigen Affinity Purified; chromodomain helicase DNA binding protein 1; anti-CHD1 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: Rabbit IgG
• Specificity: Human CHD1
• Purity/Purification: Protein A & Antigen Affinity
• Form/Format: Liquid; 0.2um filtered solution in PBS

• Applicable Applications for anti-CHD1 antibody: Immunohistochemistry-Paraffin (IHC-P)
• Application Notes: IHC-P: 1:200-1:500
• Immunogen: A synthetic peptide corresponding to the N-terminus of the Human CHD1
• Conjugation: Unconjugated
• Preparation: Produced in rabbits immunized with a synthetic peptide corresponding to the N-terminus of the Human CHD1, and purified by antigen affinity chromatography.
• Preparation and Storage: This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Immunohistochemistry (IHC)

(Immunochemical staining CHD1 in human kidney with rabbit polyclonal antibody (1:300, formalin-fixed paraffin embedded sections).)

Immunohistochemistry (IHC)

(Immunochemical staining CHD1 in mouse kidney with rabbit polyclonal antibody (1:300, formalin-fixed paraffin embedded sections).)

Related Product Information for anti-CHD1 antibody

The protein CHD1 is a member of the family of ATPase-dependent chromatin remodeling factors. CHD1, which recognizes trimethylated histone H3 lysine 4, has been implicated in transcriptional activation in organisms ranging from yeast to humans. The conserved chromatin remodeling and assembly factor CHD1 (chromodomains, helicase, DNA-binding domain) is present at active genes where it participates in histone turnover and recycling during transcription. CHD family member, CHD1 protein, also interacts with the influenza virus polymerase complex. CHD1 recognizes the H3K4me3 (histone 3 with a trimethyl group in lysine 4) histone modification, a hallmark of active chromatin. Downregulation of CHD1 causes a reduction in viral polymerase activity, viral RNA transcription, and the production of infectious particles. CHD1 associated with RNAP II and paralleled its degradation during infection with viruses that induce full or reduced degradation. Chromodomain helicase DNA-binding protein 1 (CHD1) is an ATP-dependent chromatin remodelling protein that is conserved throughout eukaryotes and has an ability to assemble and organise nucleosomes both in vitro and in vivo. The CHD1 gene, encoding the chromo-domain helicase DNA-binding protein-1, is one of the most frequently deleted genes in prostate cancer.

NCBI and Uniprot Product Information

• NCBI GI #: 239985588
• NCBI GeneID: 12648
• NCBI Accession #: NP_031716.2
• NCBI GenBank Nucleotide #: NM_007690.3
• UniProt Accession #: P40201; Q14BJ0
• Molecular Weight: 196,385 Da
• NCBI Official Full Name: chromodomain-helicase-DNA-binding protein 1
• NCBI Official Synonym Full Names: chromodomain helicase DNA binding protein 1
• NCBI Official Symbol: Chd1
• NCBI Official Synonym Symbols: AI851787; AW555109; 4930525N21Rik
• NCBI Protein Information: chromodomain-helicase-DNA-binding protein 1; CHD-1; ATP-dependent helicase CHD1
• UniProt Protein Name: Chromodomain-helicase-DNA-binding protein 1
• Protein Family: Chromodomain-helicase-DNA-binding protein
• UniProt Gene Name: Chd1
• UniProt Synonym Gene Names: Chd-1; CHD-1
• UniProt Entry Name: CHD1_MOUSE