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Immunohistochemistry (IHC)
(Anti-CD23 Picoband antibody, MBS176936-1.JPGIHC(P): Human Tonsil Tissue )
Rabbit CD23 Polyclonal Antibody | anti-FCER2 antibody
Anti-CD23 Antibody
Gene Names
Fcer2a; CD23; Fce2; Fcer2; Ly-42
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunohistochemistry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Flow Cytometry, ELISA
Purity
Immunogen affinity purified.
Synonyms
CD23; Polyclonal Antibody; Anti-CD23 Antibody; Low affinity immunoglobulin epsilon Fc receptor; Fc fragment of IgE; low affinity II; receptor for (CD23); Blast 2 antibody; BLAST-2 antibody; Blast2 antibody; C type lectin domain family 4 member J antibody; C-type lectin domain family 4 member J antibody; C-type lectin domain family 4; member J antibody; CD 23 antibody; CD 23A antibody; CD23 antibody; CD23 antigen antibody; CD23A antibody; CLEC 4J antibody; CLEC4J antibody; Fc epsilon RII antibody; Fc fragment of IgE low affinity II receptor for antibody; receptor for (CD23) antibody; Fc of IgE; Fc receptor IgE low affinity II alpha polypeptide antibody; Fc receptor; IgE; alpha polypeptide; isoform CRA_a antibody; Fc-epsilon-RII antibody; FCE 2 antibody; FCE2 antibody; FCER 2 antibody; Fcer2 antibody; FCER2_HUMAN antibody; FCER2A antibody; FceRII antibody; IgE binding factor antibody; IgE receptor lymphocyte antibody; IgE-binding factor antibody; IGEBF antibody; Immunoglobulin E binding factor antibody; Immunoglobulin E receptor; low affinity II antibody; Immunoglobulin E-binding factor antibody; LEUKOCYTE ANTIGEN CD23 antibody; Low Affinity IgE Receptor antibody; Low affinity immunoglobulin epsilon Fc receptor antibody; Low affinity immunoglobulin epsilon Fc receptor membrane bound form antibody; Low affinity immunoglobulin epsilon Fc receptor soluble form antibody; Ly-42 antibody; Ly42 antibody; Lymphocyte antigen CD23 antibody; Lymphocyte IgE receptor antibody; MGC93219 antibody; anti-FCER2 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Immunogen affinity purified.
Form/Format
Lyophilized
Sequence Length
331
Applicable Applications for anti-FCER2 antibody
Western Blot (WB), Immunohistochemistry (Paraffin-embedded Section) (IHC-P), Immunohistochemistry (frozen section) (IHC-F), Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FC), ELISA
Application Notes
WB: Concentration: 0.1-0.5ug/ml; Tested Species: Mouse, Rat
IHC-P: Concentration: 0.5-1ug/ml; Tested Species: Human, Mouse, Rat; Antigen Retrieval; By Heat
IHC-F: Concentration: 0.5-1ug/ml; Tested Species: Mouse
ICC: Concentration: 0.5-1ug/ml; Tested Species: Human
IF: Concentration: 2ug/ml; Tested Species: Mouse
FC: Concentration: 1-3ug/1x106 cell; Tested Species: Human
ELISA: Concentration: 1-5ug/ml; Tested Species: Mouse
WB: The detection limit for CD23 is approximately 0.25ng/lane under reducing conditions.
Tested Species: In house tested species with positive results.
By Heat: Boiling the paraffin sections in 1mM citrate buffer, pH6.0, for 20mins is required for staining of formalin/paraffin sections.
Other applications have not been tested.
IHC-P: Concentration: 0.5-1ug/ml; Tested Species: Human, Mouse, Rat; Antigen Retrieval; By Heat
IHC-F: Concentration: 0.5-1ug/ml; Tested Species: Mouse
ICC: Concentration: 0.5-1ug/ml; Tested Species: Human
IF: Concentration: 2ug/ml; Tested Species: Mouse
FC: Concentration: 1-3ug/1x106 cell; Tested Species: Human
ELISA: Concentration: 1-5ug/ml; Tested Species: Mouse
WB: The detection limit for CD23 is approximately 0.25ng/lane under reducing conditions.
Tested Species: In house tested species with positive results.
By Heat: Boiling the paraffin sections in 1mM citrate buffer, pH6.0, for 20mins is required for staining of formalin/paraffin sections.
Other applications have not been tested.
Immunogen
E Coli-derived mouse CD23 recombinant protein (Position: E50-P331). Mouse CD23 shares 52% amino acid (aa) sequence identity with human CD23.
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
Immunohistochemistry (IHC)
(Anti-CD23 Picoband antibody, MBS176936-1.JPGIHC(P): Human Tonsil Tissue )
Immunohistochemistry (IHC)
(Anti-CD23 Picoband antibody, MBS176936-1.JPGIHC(P): Human Tonsil Tissue )
Immunohistochemistry (IHC)
(Anti-CD23 Picoband antibody, MBS176936-2.JPGIHC(P): Mouse Spleen Tissue )
Immunohistochemistry (IHC)
(Anti-CD23 Picoband antibody, MBS176936-2.JPGIHC(P): Mouse Spleen Tissue )
Immunohistochemistry (IHC)
(Anti-CD23 Picoband antibody, MBS176936-3.JPGIHC(P): Rat Spleen Tissue )
Immunohistochemistry (IHC)
(Anti-CD23 Picoband antibody, MBS176936-3.JPGIHC(P): Rat Spleen Tissue )
Western Blot (WB)
(Anti-CD23 Picoband antibody, MBS176936-4.jpgAll lanes: Anti-CD23(MBS176936) at 0.5ug/mlWB: Mouse Liver Tissue Lysate at 40ugPredicted bind size: 37KDObserved bind size: 37KD )
Western Blot (WB)
(Anti-CD23 Picoband antibody, MBS176936-4.jpgAll lanes: Anti-CD23(MBS176936) at 0.5ug/mlWB: Mouse Liver Tissue Lysate at 40ugPredicted bind size: 37KDObserved bind size: 37KD )
Related Product Information for anti-FCER2 antibody
Description: Rabbit IgG polyclonal antibody for Low affinity immunoglobulin epsilon Fc receptor(FCER2) detection. Tested with WB, IHC-P in Human, Mouse, Rat.
Background: CD23, also known as Fc epsilon RII, or FcepsilonRII, is the "low-affinity" receptor for IgE, an antibody isotype involved in allergy and resistance to parasites, and is important in regulation of IgE levels. There are two forms of CD23: CD23a and CD23b. CD23a is present on follicular B cells, whereas CD23b requires IL-4 to be expressed on T-cells, monocytes, Langerhans cells, eosinophils, and macrophages. As part of a mapping of multiple probes to specific bands on chromosome 19 by fluorescence in situ hybridization, the FCE2 gene was assigned to 19p13.3. CD23 (FCE2) is a key molecule for B-cell activation and growth. It is the low-affinity receptor for IgE. The truncated molecule can be secreted, then functioning as a potent mitogenic growth factor.
Background: CD23, also known as Fc epsilon RII, or FcepsilonRII, is the "low-affinity" receptor for IgE, an antibody isotype involved in allergy and resistance to parasites, and is important in regulation of IgE levels. There are two forms of CD23: CD23a and CD23b. CD23a is present on follicular B cells, whereas CD23b requires IL-4 to be expressed on T-cells, monocytes, Langerhans cells, eosinophils, and macrophages. As part of a mapping of multiple probes to specific bands on chromosome 19 by fluorescence in situ hybridization, the FCE2 gene was assigned to 19p13.3. CD23 (FCE2) is a key molecule for B-cell activation and growth. It is the low-affinity receptor for IgE. The truncated molecule can be secreted, then functioning as a potent mitogenic growth factor.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Official Full Name
Low affinity immunoglobulin epsilon Fc receptor
NCBI Official Synonym Full Names
Fc receptor, IgE, low affinity II, alpha polypeptide
NCBI Official Symbol
Fcer2a
NCBI Official Synonym Symbols
CD23; Fce2; Fcer2; Ly-42
NCBI Protein Information
low affinity immunoglobulin epsilon Fc receptor; FC epsilon RII; fc-epsilon-RII; lymphocyte IgE receptor; low-affinity IgE receptor
UniProt Protein Name
Low affinity immunoglobulin epsilon Fc receptor
Protein Family
UniProt Gene Name
Fcer2
UniProt Synonym Gene Names
Fcer2a
UniProt Entry Name
FCER2_MOUSE
Uniprot Description
FCER2: Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B-cells (it is a B-cell-specific antigen).
Protein type: Membrane protein, integral
Cellular Component: membrane; plasma membrane; integral to membrane; external side of plasma membrane
Molecular Function: metal ion binding; IgE binding; carbohydrate binding
Biological Process: positive regulation of humoral immune response mediated by circulating immunoglobulin; positive regulation of nitric-oxide synthase activity; positive regulation of killing of cells of another organism; positive regulation of nitric-oxide synthase biosynthetic process
Research Articles on FCER2
Similar Products
Product Notes
The FCER2 fcer2 (Catalog #AAA176936) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-CD23 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CD23 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (Paraffin-embedded Section) (IHC-P), Immunohistochemistry (frozen section) (IHC-F), Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FC), ELISA. WB: Concentration: 0.1-0.5ug/ml; Tested Species: Mouse, Rat IHC-P: Concentration: 0.5-1ug/ml; Tested Species: Human, Mouse, Rat; Antigen Retrieval; By Heat IHC-F: Concentration: 0.5-1ug/ml; Tested Species: Mouse ICC: Concentration: 0.5-1ug/ml; Tested Species: Human IF: Concentration: 2ug/ml; Tested Species: Mouse FC: Concentration: 1-3ug/1x106 cell; Tested Species: Human ELISA: Concentration: 1-5ug/ml; Tested Species: Mouse WB: The detection limit for CD23 is approximately 0.25ng/lane under reducing conditions. Tested Species: In house tested species with positive results. By Heat: Boiling the paraffin sections in 1mM citrate buffer, pH6.0, for 20mins is required for staining of formalin/paraffin sections. Other applications have not been tested. Researchers should empirically determine the suitability of the FCER2 fcer2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD23, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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