Western Blot (WB)
(Anti- c-Rel Picoband antibody, MBS178033, Western blottingAll lanes: Anti c-Rel (MBS178033) at 0.5ug/mlLane 1: Rat Kidney Tissue Lysate at 50ugLane 2: HELA Whole Cell Lysate at 40ugPredicted bind size: 69KDObserved bind size: 69KD )
c-Rel Polyclonal Antibody | anti-c-Rel antibody
Anti-c-Rel Antibody
Immunohistochemistry (IHC) Paraffin Concentration: 0.5-1ug/ml
Western Blot (WB)
(Anti- c-Rel Picoband antibody, MBS178033, Western blottingAll lanes: Anti c-Rel (MBS178033) at 0.5ug/mlLane 1: Rat Kidney Tissue Lysate at 50ugLane 2: HELA Whole Cell Lysate at 40ugPredicted bind size: 69KDObserved bind size: 69KD )
Western Blot (WB)
(Anti- c-Rel Picoband antibody, MBS178033, Western blottingAll lanes: Anti c-Rel (MBS178033) at 0.5ug/mlLane 1: Rat Kidney Tissue Lysate at 50ugLane 2: HELA Whole Cell Lysate at 40ugPredicted bind size: 69KDObserved bind size: 69KD )
Immunohistochemistry (IHC)
(Anti- c-Rel Picoband antibody, MBS178033,IHC(P)IHC(P): Mouse Intestine Tissue)
Immunohistochemistry (IHC)
(Anti- c-Rel Picoband antibody, MBS178033,IHC(P)IHC(P): Mouse Intestine Tissue)
Immunohistochemistry (IHC)
(Anti- c-Rel Picoband antibody, MBS178033,IHC(P)IHC(P): Rat Intestine Tissue )
Immunohistochemistry (IHC)
(Anti- c-Rel Picoband antibody, MBS178033,IHC(P)IHC(P): Rat Intestine Tissue )
Immunohistochemistry (IHC)
(Anti- c-Rel Picoband antibody, MBS178033,IHC(P)IHC(P): Human Mammary Cancer Tissue )
Immunohistochemistry (IHC)
(Anti- c-Rel Picoband antibody, MBS178033,IHC(P)IHC(P): Human Mammary Cancer Tissue )
Background: The proto-oncogene c-Rel is a protein that in humans is encoded by the REL gene. This gene is mapped to chromosome 2p13-p12. The c-Rel protein is a member of the NF-kappaB family of transcription factors and contains a Rel homology domain (RHD) at its N-terminus and two C-terminal transactivation domains. c-Rel has an important role in B-cell survival and proliferation. The REL gene is amplified or mutated in several human B-cell lymphomas, including diffuse large B-cell lymphoma and Hodgkin's lymphoma.
NCBI and Uniprot Product Information
Uniprot Description
REL: a proto-oncogenic transcription factor of the nuclear factor-kappaB (NFkB) group. There are five NFkB proteins in mammals (RelA/NFkB-p65, RelB, c-Rel, NF-_B1/NFkB-p105, and NF-_B2/NFkB-p100). They form a variety of homodimers and heterodimers, each of which activates its own characteristic set of genes. May play a role in differentiation and lymphopoiesis.
Protein type: Oncoprotein; Transcription factor
Cellular Component: cytoplasm; cytosol; nucleus; transcription factor complex
Molecular Function: chromatin binding; DNA binding; protein binding; sequence-specific DNA binding; transcription factor activity
Biological Process: cellular response to stress; cytokine production; I-kappaB kinase/NF-kappaB cascade; inflammatory response; innate immune response; negative regulation of interferon-beta production; negative regulation of transcription from RNA polymerase II promoter; positive regulation of interleukin-12 biosynthetic process; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; regulation of transcription, DNA-dependent; response to cytokine stimulus; transcription from RNA polymerase II promoter; transcription, DNA-dependent
Research Articles on c-Rel
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Product Notes
The c-Rel rel (Catalog #AAA178033) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The Anti-c-Rel Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's c-Rel can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC) Paraffin. Western Blot Concentration: 0.1-0.5ug/ml Immunohistochemistry (IHC) Paraffin Concentration: 0.5-1ug/ml. Researchers should empirically determine the suitability of the c-Rel rel for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "c-Rel, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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