Western Blot
(All lanes: anoctamin 2 antibody at 2ug/ml+ mouse brain tissue secondary Secondary Goat polyclonal to Rabbit IgG at 1/15000 dilution Predicted band size : 114 kDa Observed band size: 114 kDa )
Rabbit anoctamin 2 Polyclonal Antibody | anti-ANO2 antibody
Rabbit anti-human anoctamin 2 polyclonal Antibody
Western Blot
(All lanes: anoctamin 2 antibody at 2ug/ml+ mouse brain tissue secondary Secondary Goat polyclonal to Rabbit IgG at 1/15000 dilution Predicted band size : 114 kDa Observed band size: 114 kDa )
Western Blot
(All lanes: anoctamin 2 antibody at 2ug/ml+ mouse brain tissue secondary Secondary Goat polyclonal to Rabbit IgG at 1/15000 dilution Predicted band size : 114 kDa Observed band size: 114 kDa )
Immunohistochemistry
(Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using MBS714387 at dilution 1:50.)
Immunohistochemistry
(Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using MBS714387 at dilution 1:50.)
Immunofluorescence
(Immunofluorescent analysis of HepG2 cells, using MBS714387 at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). )
Immunofluorescence
(Immunofluorescent analysis of HepG2 cells, using MBS714387 at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). )
Immunoprecipitation
( IP Result of anti-ANO2 (IP: MBS714387 , 4ug; Detection: MBS714387 1:300) with mouse brain tissue lysate 10000ug. )
Immunoprecipitation
( IP Result of anti-ANO2 (IP: MBS714387 , 4ug; Detection: MBS714387 1:300) with mouse brain tissue lysate 10000ug. )
Calcium-activated chloride channel (CaCC) which may play a role in olfactory signal transduction. Odorant molecules bind to odor-sensing receptors (OSRs), leading to an increase in calcium entry that activates CaCC current which amplifies the depolarization of the OSR cells, ANO2 seems to be theunderlying chloride channel involved in this process. May mediate light perception amplification in retina.
NCBI and Uniprot Product Information
NCBI Description
ANO2 belongs to a family of calcium-activated chloride channels (CaCCs) (reviewed by Hartzell et al., 2009 [PubMed 19015192]).[supplied by OMIM, Jan 2011]
Uniprot Description
ANO2: Acts as a calcium-activated chloride channel (CaCC), mostly in photoreceptors. May mediate olfactory amplification in olfactory sensory neurons (OSNs) and light perception amplification in retina. Belongs to the anoctamin family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Transporter, ion channel; Membrane protein, multi-pass; Transporter
Chromosomal Location of Human Ortholog: 12p13.3
Cellular Component: nucleoplasm; nonmotile primary cilium; plasma membrane
Molecular Function: protein homodimerization activity; intracellular calcium activated chloride channel activity; protein heterodimerization activity
Biological Process: transmembrane transport
Research Articles on ANO2
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Product Notes
The ANO2 ano2 (Catalog #AAA714387) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-human anoctamin 2 polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's anoctamin 2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunofluorescence (IF). Researchers should empirically determine the suitability of the ANO2 ano2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "anoctamin 2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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