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Immunohistochemistry (IHC) (Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE))

Rabbit anti-Human ANO2 Polyclonal Antibody | anti-ANO2 antibody

ANO2, NT (TMEM16B, Anoctamin-2, Transmembrane Protein 16B, C12orf3)

Gene Names
ANO2; C12orf3; TMEM16B
Reactivity
Human
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Affinity Purified
Purified by immunoaffinity chromatography.
Synonyms
ANO2; Polyclonal Antibody; NT (TMEM16B; Anoctamin-2; Transmembrane Protein 16B; C12orf3); Anti -ANO2; anti-ANO2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
Recognizes human ANO2. Species sequence homology: mouse and rat.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Form/Format
Supplied as a liquid in PBS, 0.02% sodium azide.
Applicable Applications for anti-ANO2 antibody
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
Suitable for use in ELISA, Western Blot and Immunohistochemistry.
Dilution: Western Blot: 1-2ug/ml
Immunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml
Immunogen
Synthetic peptide corresponding to 19aa from human TMEM16B at N-terminus.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Immunohistochemistry (IHC)

(Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE))

Immunohistochemistry (IHC) (Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE))

Immunohistochemistry (IHC)

(Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE))

Immunohistochemistry (IHC) (Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE))

Western Blot (WB)

(Western blot analysis of TMEM16B in rat brain tissue lysate with TMEM16B antibody at (A) 1 and (B) 2ug/ml.)

Western Blot (WB) (Western blot analysis of TMEM16B in rat brain tissue lysate with TMEM16B antibody at (A) 1 and (B) 2ug/ml.)
Related Product Information for anti-ANO2 antibody
Acts as a calcium-activated chloride channel (CaCC), mostly in photoreceptors. May mediate olfactory amplification in olfactory sensory neurons (OSNs) and light perception amplification in retina.
Product Categories/Family for anti-ANO2 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
113,969 Da
NCBI Official Full Name
anoctamin-2 isoform 2
NCBI Official Synonym Full Names
anoctamin 2
NCBI Official Symbol
ANO2
NCBI Official Synonym Symbols
C12orf3; TMEM16B
NCBI Protein Information
anoctamin-2; transmembrane protein 16B (eight membrane-spanning domains)
UniProt Protein Name
Anoctamin-2
Protein Family
UniProt Gene Name
ANO2
UniProt Synonym Gene Names
C12orf3; TMEM16B
UniProt Entry Name
ANO2_HUMAN

NCBI Description

ANO2 belongs to a family of calcium-activated chloride channels (CaCCs) (reviewed by Hartzell et al., 2009 [PubMed 19015192]).[supplied by OMIM, Jan 2011]

Uniprot Description

ANO2: Acts as a calcium-activated chloride channel (CaCC), mostly in photoreceptors. May mediate olfactory amplification in olfactory sensory neurons (OSNs) and light perception amplification in retina. Belongs to the anoctamin family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Transporter; Membrane protein, multi-pass; Transporter, ion channel; Membrane protein, integral

Chromosomal Location of Human Ortholog: 12p13.3

Cellular Component: nucleoplasm; nonmotile primary cilium; plasma membrane

Molecular Function: protein homodimerization activity; intracellular calcium activated chloride channel activity; protein heterodimerization activity

Biological Process: transmembrane transport

Research Articles on ANO2

Similar Products

Product Notes

The ANO2 ano2 (Catalog #AAA645178) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ANO2, NT (TMEM16B, Anoctamin-2, Transmembrane Protein 16B, C12orf3) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ANO2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC). Suitable for use in ELISA, Western Blot and Immunohistochemistry. Dilution: Western Blot: 1-2ug/ml Immunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml. Researchers should empirically determine the suitability of the ANO2 ano2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ANO2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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