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NT5C3A/NT5C3 Recombinant Protein | NT5C3A recombinant protein
NT5C3A/NT5C3 Protein, Human, Recombinant
Purity
>92% as determined by SDS-PAGE
Synonyms
NT5C3A/NT5C3; NT5C3A/NT5C3 Protein; Human; Recombinant; Human NT5C3 Protein; cN-III Protein; hUMP1 Protein; NT5C3 Protein; p36 Protein; P5'N-1 Protein; P5N-1 Protein; P5N1 Protein; PN-I Protein; POMP Protein; PSN1 Protein; UMPH Protein; UMPH1 Protein; 5'-nucleotidase; cytosolic IIIA; NT5C3A recombinant protein
Host
E Coli
Purity/Purification
>92% as determined by SDS-PAGE
Form/Format
Lyophilized from sterile PBS. Normally 5%-8% trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
Sequence
Met12-Leu297
Species
Human
Predicted N Terminal
Met 12
Tag
Native
Protein Construction
A DNA sequence encoding the mature form of human NT5C3 (NP_001002010)(Met 12-Leu 297) was expressed.
Reconstitution
A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
Preparation and Storage
Samples are stable for up to twelve months from date of receipt at -20 degree C to -80 degree C. Store it under sterile conditions at -20 degree C to -80 degree C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid.
They are shipped out with blue ice.
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid.
They are shipped out with blue ice.
SDS-Page
SDS-Page
Related Product Information for NT5C3A recombinant protein
Background: NT5C3A (5'-Nucleotidase, Cytosolic IIIA) is a Protein Coding gene. This gene encodes a member of the 5'-nucleotidase family of enzymes that catalyze the dephosphorylation of nucleoside 5'-monophosphates. The encoded protein is the type 1 isozyme of pyrimidine 5' nucleotidase and catalyzes the dephosphorylation of pyrimidine 5' monophosphates. NT5C3A expression required both an intronic IFN-stimulated response element and the IFN-stimulated transcription factor IRF1. Overexpression of NT5C3A, but not of its catalytic mutants, suppressed IL-8 production by HEK293 cells. NT5C3A-stimulated sirtuin activity resulted in deacetylation of histone H3 and the NF-kappaB subunit RelA (also known as p65), both of which were associated with the proximal region of the Il8 promoter, thus repressing the transcription of Il8 Together.
NCBI and Uniprot Product Information
Molecular Weight
The recombinant human NT5C3 consists of 286 amino acids and predicts a molecular mass of 32.7KDa. It migrates as an approximately 32kDa band in SDS-PAGE under reducing conditions.
Protein Family
Similar Products
Product Notes
The NT5C3A (Catalog #AAA8121567) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: Met12-Leu2 97. It is sometimes possible for the material contained within the vial of "NT5C3A/NT5C3, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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