Immunohistochemistry (IHC)
(Anti-ALOX15 Picoband antibody, MBS176844-1.JPGIHC(P): Mouse Lung Tissue )
Rabbit anti-Human ALOX15 Polyclonal Antibody | anti-ALOX15 antibody
Anti-ALOX15 Antibody
Immunohistochemistry (IHC)
(Anti-ALOX15 Picoband antibody, MBS176844-1.JPGIHC(P): Mouse Lung Tissue )
Immunohistochemistry (IHC)
(Anti-ALOX15 Picoband antibody, MBS176844-1.JPGIHC(P): Mouse Lung Tissue )
Immunohistochemistry (IHC)
(Anti-ALOX15 Picoband antibody, MBS176844-2.JPGIHC(P): Rat Lung Tissue )
Immunohistochemistry (IHC)
(Anti-ALOX15 Picoband antibody, MBS176844-2.JPGIHC(P): Rat Lung Tissue )
Immunohistochemistry (IHC)
(Anti-ALOX15 Picoband antibody, MBS176844-3.JPGIHC(P): Human Intestine Cancer Tissue )
Immunohistochemistry (IHC)
(Anti-ALOX15 Picoband antibody, MBS176844-3.JPGIHC(P): Human Intestine Cancer Tissue )
Immunohistochemistry (IHC)
(Anti-ALOX15 Picoband antibody, MBS176844-4.JPGIHC(P): Human Mammary Cancer Tissue )
Immunohistochemistry (IHC)
(Anti-ALOX15 Picoband antibody, MBS176844-4.JPGIHC(P): Human Mammary Cancer Tissue )
Western Blot (WB)
(Anti-ALOX15 Picoband antibody, MBS176844-5.jpgAll lanes: Anti-ALOX15(MBS176844) at 0.5ug/mWB: Recombinant Human ALOX15 Protein 0.5ngPredicted bind size: 39KDObserved bind size: 39KD )
Western Blot (WB)
(Anti-ALOX15 Picoband antibody, MBS176844-5.jpgAll lanes: Anti-ALOX15(MBS176844) at 0.5ug/mWB: Recombinant Human ALOX15 Protein 0.5ngPredicted bind size: 39KDObserved bind size: 39KD )
Background: Arachidonate 15-lipoxygenase, also known as 15 LOX or LOG15, is an enzyme that in humans is encoded by the ALOX15 gene. This gene is mapped to 17p13.2. It is found that ALOX15 is a mutator gene. ALOX15 gene product is implicated in antiinflammation, membrane remodeling, and cancer development/metastasis. Loss of the TP53 gene, or gain-of-function activities resulting from the expression of its mutant forms regulates ALOX15 promoter activity in human and in mouse, albeit in directionally opposite manners.
NCBI and Uniprot Product Information
Uniprot Description
ALOX15: Converts arachidonic acid to 15S- hydroperoxyeicosatetraenoic acid. Also acts on C-12 of arachidonate as well as on linoleic acid. Belongs to the lipoxygenase family.
Protein type: EC 1.13.11.33; EC 1.13.11.31; Motility/polarity/chemotaxis; Lipid Metabolism - arachidonic acid; Lipid Metabolism - linoleic acid; Oxidoreductase
Chromosomal Location of Human Ortholog: 17p13.3
Cellular Component: extrinsic to internal side of plasma membrane; membrane; plasma membrane; lipid particle; cytosol
Molecular Function: arachidonate 12-lipoxygenase activity; protein binding; hepoxilin A3 synthase activity; phosphatidylinositol-4,5-bisphosphate binding; arachidonate 15-lipoxygenase activity; hepoxilin-epoxide hydrolase activity; iron ion binding
Biological Process: ossification; positive regulation of heterotypic cell-cell adhesion; positive regulation of actin filament polymerization; wound healing; lipoxygenase pathway; negative regulation of adaptive immune response; phosphatidylethanolamine biosynthetic process; arachidonic acid metabolic process; leukotriene metabolic process; hepoxilin biosynthetic process; inflammatory response; apoptotic cell clearance; bone mineralization
Research Articles on ALOX15
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Product Notes
The ALOX15 alox15 (Catalog #AAA176844) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-ALOX15 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ALOX15 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC) Paraffin. Researchers should empirically determine the suitability of the ALOX15 alox15 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ALOX15, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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