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Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human gasrtic cancer tissue using ALOX15 Polyclonal Antibody at dilution 1:50)

Rabbit ALOX15 Polyclonal Antibody | anti-ALOX15 antibody

ALOX15 Polyclonal Antibody

Gene Names
ALOX15; 12-LOX; 15LOX-1; 15-LOX-1
Reactivity
Human, Mouse, Rat
Applications
ELISA, Immunohistochemistry
Purity
Antigen affinity purification
Synonyms
ALOX15; Polyclonal Antibody; ALOX15 Polyclonal Antibody; 12-LOX; L-12LO; anti-ALOX15 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen affinity purification
Concentration
2.3mg/mL (varies by lot)
Sequence Length
662
Applicable Applications for anti-ALOX15 antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes
IHC: 1:50-1:200
Immunogen
Synthetic peptide of human ALOX15
Buffer
PBS with 0.05% sodium azide, 50% glycerol, pH7.3
Preparation and Storage
Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human gasrtic cancer tissue using ALOX15 Polyclonal Antibody at dilution 1:50)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human gasrtic cancer tissue using ALOX15 Polyclonal Antibody at dilution 1:50)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human liver cancer tissue using ALOX15 Polyclonal Antibody at dilution 1:50)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human liver cancer tissue using ALOX15 Polyclonal Antibody at dilution 1:50)
Related Product Information for anti-ALOX15 antibody
Arachidonate 15-lipoxygenase is an enzyme that in humans is encoded by the ALOX15 gene. Non-heme iron-containing dioxygenase that catalyzes the stereo-specific peroxidation of free and esterified polyunsaturated fatty acids generating a spectrum of bioactive lipid mediators. Converts arachidonic acid into 12-hydroperoxyeicosatetraenoic acid/12-HPETE and 15-hydroperoxyeicosatetraenoic acid/15-HPETE. Also converts linoleic acid to 13-hydroperoxyoctadecadienoic acid. May also act on (12S)-hydroperoxyeicosatetraenoic acid/(12S)-HPETE to produce hepoxilin A3.
Product Categories/Family for anti-ALOX15 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
246
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
70,108 Da
NCBI Official Full Name
arachidonate 15-lipoxygenase
NCBI Official Synonym Full Names
arachidonate 15-lipoxygenase
NCBI Official Symbol
ALOX15
NCBI Official Synonym Symbols
12-LOX; 15LOX-1; 15-LOX-1
NCBI Protein Information
arachidonate 15-lipoxygenase; 12/15-lipoxygenase; 15-LOX; 15-lipooxygenase-1; arachidonate 12-lipoxygenase, leukocyte-type; arachidonate omega-6 lipoxygenase
UniProt Protein Name
Arachidonate 15-lipoxygenase
UniProt Gene Name
ALOX15
UniProt Synonym Gene Names
LOG15; 15-LOX; 15-LOX-1; 12-LOX
UniProt Entry Name
LOX15_HUMAN

Uniprot Description

ALOX15: Converts arachidonic acid to 15S- hydroperoxyeicosatetraenoic acid. Also acts on C-12 of arachidonate as well as on linoleic acid. Belongs to the lipoxygenase family.

Protein type: Motility/polarity/chemotaxis; Lipid Metabolism - arachidonic acid; Oxidoreductase; Lipid Metabolism - linoleic acid; EC 1.13.11.33; EC 1.13.11.31

Chromosomal Location of Human Ortholog: 17p13.3

Cellular Component: extrinsic to internal side of plasma membrane; membrane; plasma membrane; lipid particle; cytosol

Molecular Function: protein binding; phosphatidylinositol-4,5-bisphosphate binding; arachidonate 12-lipoxygenase activity; hepoxilin A3 synthase activity; arachidonate 15-lipoxygenase activity; hepoxilin-epoxide hydrolase activity; iron ion binding

Biological Process: ossification; positive regulation of heterotypic cell-cell adhesion; wound healing; phosphatidylethanolamine biosynthetic process; leukotriene metabolic process; bone mineralization; positive regulation of actin filament polymerization; lipoxygenase pathway; negative regulation of adaptive immune response; arachidonic acid metabolic process; hepoxilin biosynthetic process; inflammatory response; apoptotic cell clearance

Research Articles on ALOX15

Similar Products

Product Notes

The ALOX15 alox15 (Catalog #AAA2525388) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ALOX15 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's ALOX15 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). IHC: 1:50-1:200. Researchers should empirically determine the suitability of the ALOX15 alox15 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ALOX15, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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