Human PITPNM family member 3 ELISA Kit | PITPNM3 elisa kit

Human Membrane-associated phosphatidylinositol transfer protein 3, PITPNM3 ELISA Kit

Cat. Num. AAA9320106

• Gene Names: PITPNM3; NIR1; ACKR6; CORD5; RDGBA3; PITPNM3
• Reactivity: Human
• Synonyms: PITPNM family member 3; Human Membrane-associated phosphatidylinositol transfer protein 3; PITPNM3 ELISA Kit; Human Membrane-associated phosphatidylinositol transfer protein 3 (PITPNM3) ELISA kit; CORD5; MGC157740; MGC157741; NIR1; RDGBA3; PYK2 N-terminal domain-interacting receptor 1; membrane-associated phosphatidylinositol transfer protein 3; retinal degeneration B alpha 3; PITPNM3 elisa kit

• Reactivity: Human

• Preparation and Storage: Store all reagents at 2-8 degree C

NCBI and Uniprot Product Information

• NCBI GI #: 190358515
• NCBI GeneID: 83394
• NCBI Accession #: NP_112497.2
• NCBI GenBank Nucleotide #: NM_031220.3
• UniProt Accession #: Q9BZ71; Q59GH9; Q9NPQ4; A1A5D0; F8WEW5
• Molecular Weight: 106,781 Da
• NCBI Official Full Name: membrane-associated phosphatidylinositol transfer protein 3 isoform 1
• NCBI Official Synonym Full Names: PITPNM family member 3
• NCBI Official Symbol: PITPNM3
• NCBI Official Synonym Symbols: NIR1; ACKR6; CORD5; RDGBA3; PITPNM3
• NCBI Protein Information: membrane-associated phosphatidylinositol transfer protein 3; NIR-1; PITPnm 3; cone rod dystrophy 5; atypical chemokine receptor 6; retinal degeneration B alpha 3; PYK2 N-terminal domain-interacting receptor 1; phosphatidylinositol transfer protein, membrane-associated 3
• UniProt Protein Name: Membrane-associated phosphatidylinositol transfer protein 3
• Protein Family: Membrane-associated phosphatidylinositol transfer protein
• UniProt Gene Name: PITPNM3
• UniProt Synonym Gene Names: NIR1; PITPnm 3; NIR-1
• UniProt Entry Name: PITM3_HUMAN

NCBI Description

This gene encodes a member of a family of membrane-associated phosphatidylinositol transfer domain-containing proteins. The calcium-binding protein has phosphatidylinositol (PI) transfer activity and interacts with the protein tyrosine kinase PTK2B (also known as PYK2). The protein is homologous to a Drosophila protein that is implicated in the visual transduction pathway in flies. Mutations in this gene result in autosomal dominant cone dystrophy. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]

Uniprot Description

PITPNM3: transfers phosphatidylinositol and phosphatidylcholine between membranes. Binds calcium ions. Interacts with Pyk2 via its C-terminus. Two splice-variant isoforms have been described.

Protein type: Calcium-binding

Chromosomal Location of Human Ortholog: 17p13

Cellular Component: integral to membrane; endomembrane system; intracellular

Molecular Function: protein binding; phosphatidylinositol transporter activity; calcium ion binding; receptor tyrosine kinase binding; lipid binding

Biological Process: phospholipid transport; phosphatidylinositol metabolic process

Disease: Cone-rod Dystrophy 5