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Testing Data (Sample(30 ug of whole cell lysate)A: 293TB: Raji7.5% SDS PAGEPrimary antibody diluted at 1: 1500)

Rabbit anti-Human NIR1 Polyclonal Antibody | anti-NIR1 antibody

NIR1 antibody

Gene Names
PITPNM3; NIR1; ACKR6; CORD5; RDGBA3; PITPNM3
Reactivity
Human
Applications
Western Blot
Purity
Purified by antigen-affinity chromatography.
Synonyms
NIR1; Polyclonal Antibody; NIR1 antibody; anti-NIR1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Purity/Purification
Purified by antigen-affinity chromatography.
Form/Format
Supplied in 0.1M Tris-buffered saline with 10% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative.
Sequence Length
974
Applicable Applications for anti-NIR1 antibody
Western Blot (WB)
Application Notes
Western blotting: 1:500-1:3000
Immunogen Type
Peptide
Immunogen Description
Synthetic peptide contain a sequence corresponding to a region within amino acids 912 and 974 of Human PITPNM3
Target Name
NIR1
Preparation and Storage
Store at -20 degree C for long term preservation (recommended). Store at 4 degree C for short term use.

Testing Data

(Sample(30 ug of whole cell lysate)A: 293TB: Raji7.5% SDS PAGEPrimary antibody diluted at 1: 1500)

Testing Data (Sample(30 ug of whole cell lysate)A: 293TB: Raji7.5% SDS PAGEPrimary antibody diluted at 1: 1500)
Related Product Information for anti-NIR1 antibody
PITPNM3 belongs to a family of membrane-associated phosphatidylinositol transfer domain-containing proteins that share homology with the Drosophila retinal degeneration B (rdgB) protein (Ocaka et al., 2005 [PubMed 15627748]).[supplied by OMIM]
Product Categories/Family for anti-NIR1 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
102,710 Da
NCBI Official Full Name
membrane-associated phosphatidylinositol transfer protein 3 isoform 1
NCBI Official Synonym Full Names
PITPNM family member 3
NCBI Official Symbol
PITPNM3
NCBI Official Synonym Symbols
NIR1; ACKR6; CORD5; RDGBA3; PITPNM3
NCBI Protein Information
membrane-associated phosphatidylinositol transfer protein 3
UniProt Protein Name
Membrane-associated phosphatidylinositol transfer protein 3
UniProt Gene Name
PITPNM3
UniProt Synonym Gene Names
NIR1; PITPnm 3; NIR-1
UniProt Entry Name
PITM3_HUMAN

NCBI Description

This gene encodes a member of a family of membrane-associated phosphatidylinositol transfer domain-containing proteins. The calcium-binding protein has phosphatidylinositol (PI) transfer activity and interacts with the protein tyrosine kinase PTK2B (also known as PYK2). The protein is homologous to a Drosophila protein that is implicated in the visual transduction pathway in flies. Mutations in this gene result in autosomal dominant cone dystrophy. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]

Uniprot Description

PITPNM3: transfers phosphatidylinositol and phosphatidylcholine between membranes. Binds calcium ions. Interacts with Pyk2 via its C-terminus. Two splice-variant isoforms have been described.

Protein type: Calcium-binding

Chromosomal Location of Human Ortholog: 17p13

Cellular Component: integral to membrane; endomembrane system; intracellular

Molecular Function: protein binding; phosphatidylinositol transporter activity; calcium ion binding; receptor tyrosine kinase binding; lipid binding

Biological Process: phospholipid transport; phosphatidylinositol metabolic process

Disease: Cone-rod Dystrophy 5

Research Articles on NIR1

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Product Notes

The NIR1 pitpnm3 (Catalog #AAA9408596) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NIR1 antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's NIR1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western blotting: 1:500-1:3000. Researchers should empirically determine the suitability of the NIR1 pitpnm3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NIR1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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