PCNA-associated factor Recombinant Protein | PAF15 recombinant protein
Recombinant Human PCNA-associated factor
Gene Names
PCLAF; L5; PAF; OEATC; PAF15; OEATC1; p15PAF; NS5ATP9; OEATC-1; p15/PAF; KIAA0101; p15(PAF)
Reactivity
Human
Purity
Greater than 90% as determined by SDS-PAGE.
Synonyms
PCNA-associated factor; Recombinant Human PCNA-associated factor; Hepatitis C virus NS5A-transactivated protein 9; HCV NS5A-transactivated protein 9Overexpressed in anaplastic thyroid carcinoma 1; OEATC-1; PCNA-associated factor of 15 kDa; PAF15; p15PAF; PAF15 recombinant protein
Host
E Coli
Reactivity
Human
Purity/Purification
Greater than 90% as determined by SDS-PAGE.
Form/Format
20mM Tris-HCl based buffer, pH8.0
Sequence Positions
Full Length, 1-111aa
Tag Info
GST-tag
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C. Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
Related Product Information for PAF15 recombinant protein
PCNA-binding protein that acts as a regulator of DNA repair during DNA replication. Following DNA damage, the interaction with PCNA is disrupted, facilitating the interaction between monoubiquitinated PCNA and the translesion DNA synthesis DNA polymerase eta (POLH) at stalled replisomes, facilitating the bypass of replication-fork-blocking lesions. Also acts as a regulator of centrosome number.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
39.4kD
NCBI Official Full Name
PCNA-associated factor isoform 2
NCBI Official Synonym Full Names
PCNA clamp associated factor
NCBI Official Symbol
PCLAF
NCBI Official Synonym Symbols
L5; PAF; OEATC; PAF15; OEATC1; p15PAF; NS5ATP9; OEATC-1; p15/PAF; KIAA0101; p15(PAF)
NCBI Protein Information
PCNA-associated factor
UniProt Protein Name
PCNA-associated factor
Protein Family
UniProt Gene Name
PCLAF
UniProt Synonym Gene Names
HCV NS5A-transactivated protein 9; OEATC-1; PAF15; p15PAF
Uniprot Description
PAF: May be involved in protection of cells from UV-induced cell death.
Protein type: DNA repair, damage
Chromosomal Location of Human Ortholog: 15q22.31
Cellular Component: centrosome; nucleoplasm; nucleus; perinuclear region of cytoplasm
Molecular Function: chromatin binding; protein binding
Biological Process: bypass DNA synthesis; centrosome cycle; DNA replication; regulation of cell cycle; response to DNA damage stimulus; response to UV
Research Articles on PAF15
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Product Notes
The PAF15 pclaf (Catalog #AAA9420385) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is Full Length, 1-111aa. The Recombinant Human PCNA-associated factor reacts with Human and may cross-react with other species as described in the data sheet. It is sometimes possible for the material contained within the vial of "PCNA-associated factor, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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