Western Blot (WB)
(Western Blot analysis of PGDS expression in transfected 293T cell line by PGDS polyclonal antibody. Lane 1: PGDS transfected lysate (23.3kD). Lane 2: Non-transfected lysate.)
Rabbit anti-Human PGDS Polyclonal Antibody | anti-PGDS antibody
PGDS (HPGDS, Hematopoietic Prostaglandin D Synthase, H-PGDS, GST Class-sigma, Glutathione S-transferase, Glutathione-dependent PGD Synthase, Glutathione-requiring Prostaglandin D Synthase, Prostaglandin-H2 D-isomerase, GSTS, PTGDS2) (AP)
Western Blot (WB)
(Western Blot analysis of PGDS expression in transfected 293T cell line by PGDS polyclonal antibody. Lane 1: PGDS transfected lysate (23.3kD). Lane 2: Non-transfected lysate.)
Western Blot (WB)
(Western Blot analysis of PGDS expression in transfected 293T cell line by PGDS polyclonal antibody. Lane 1: PGDS transfected lysate (23.3kD). Lane 2: Non-transfected lysate.)
NCBI and Uniprot Product Information
NCBI Description
Prostaglandin-D synthase is a sigma class glutathione-S-transferase family member. The enzyme catalyzes the conversion of PGH2 to PGD2 and plays a role in the production of prostanoids in the immune system and mast cells. The presence of this enzyme can be used to identify the differentiation stage of human megakaryocytes. [provided by RefSeq, Jul 2008]
Uniprot Description
Ptgds2: Bifunctional enzyme which catalyzes both the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation, and the conjugation of glutathione with a wide range of aryl halides and organic isothiocyanates. Also exhibits low glutathione-peroxidase activity towards cumene hydroperoxide. Belongs to the GST superfamily. Sigma family.
Protein type: EC 2.5.1.18; Lipid Metabolism - arachidonic acid; EC 5.3.99.2; Isomerase
Chromosomal Location of Human Ortholog: 4q22.3
Cellular Component: cytoplasm; cytosol
Molecular Function: prostaglandin-D synthase activity; protein homodimerization activity; glutathione transferase activity; magnesium ion binding; calcium ion binding
Biological Process: xenobiotic metabolic process; cyclooxygenase pathway; arachidonic acid metabolic process; locomotory behavior; signal transduction; prostaglandin metabolic process
Research Articles on PGDS
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Product Notes
The PGDS hpgds (Catalog #AAA6389185) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PGDS (HPGDS, Hematopoietic Prostaglandin D Synthase, H-PGDS, GST Class-sigma, Glutathione S-transferase, Glutathione-dependent PGD Synthase, Glutathione-requiring Prostaglandin D Synthase, Prostaglandin-H2 D-isomerase, GSTS, PTGDS2) (AP) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PGDS can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the PGDS hpgds for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PGDS, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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