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Mouse nudix (nucleoside diphosphate linked moiety X) -type motif 15 ELISA Kit | NUDT15 elisa kit

Mouse Probable 7, 8-dihydro-8-oxoguanine triphosphatase NUDT15, NUDT15 ELISA Kit

Gene Names
Nudt15; MTH2; 6530403O17; A730068G11Rik
Reactivity
Mouse
Synonyms
nudix (nucleoside diphosphate linked moiety X) -type motif 15; Mouse Probable 7; 8-dihydro-8-oxoguanine triphosphatase NUDT15; NUDT15 ELISA Kit; 8-dihydro-8-oxoguanine triphosphatase NUDT15 (NUDT15) ELISA kit; FLJ10956; MGC104352; MTH2; RP11-90M2.1; A730068G11Rik; nudix-type motif 15; NUDT15 elisa kit
Ordering
For Research Use Only!
Reactivity
Mouse
Sequence Length
170
Preparation and Storage
Store all reagents at 2-8 degree C

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
19,576 Da
NCBI Official Full Name
nucleotide triphosphate diphosphatase NUDT15
NCBI Official Synonym Full Names
nudix (nucleoside diphosphate linked moiety X)-type motif 15
NCBI Official Symbol
Nudt15
NCBI Official Synonym Symbols
MTH2; 6530403O17; A730068G11Rik
NCBI Protein Information
nucleotide triphosphate diphosphatase NUDT15
UniProt Protein Name
Probable 8-oxo-dGTP diphosphatase NUDT15
Protein Family
UniProt Gene Name
Nudt15
UniProt Synonym Gene Names
Mth2; 8-oxo-dGTPase NUDT15; mMTH2; Nudix motif 15
UniProt Entry Name
NUD15_MOUSE

Uniprot Description

NUDT15: Mediates the hydrolysis of some nucleoside diphosphate derivatives. Can degrade 8-oxo-dGTP in vitro, suggesting that it may remove an oxidatively damaged form of guanine (7,8-dihydro-8- oxoguanine) from DNA and the nucleotide pool, thereby preventing misincorporation of 8-oxo-dGTP into DNA thus preventing A:T to C:G transversions. Its substrate specificity in vivo however remains unclear. May have a role in DNA synthesis and cell cycle progression through the interaction with PCNA. Belongs to the Nudix hydrolase family.

Protein type: EC 3.6.1.55; Hydrolase

Molecular Function: hydrolase activity; metal ion binding; 8-oxo-7,8-dihydroguanine triphosphatase activity

Biological Process: dGTP catabolic process; response to reactive oxygen species; purine deoxyribonucleoside triphosphate catabolic process

Research Articles on NUDT15

Similar Products

Product Notes

The Mouse NUDT15 nudt15 (Catalog #AAA9320886) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9320886 ELISA Kit recognizes Mouse NUDT15. It is sometimes possible for the material contained within the vial of "nudix (nucleoside diphosphate linked moiety X) -type motif 15, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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