Western Blot (WB)
(Western Blot of analysis of extracts of rat spleen, using NUDT15 at 1:1000 dilution.)
Rabbit anti-Mouse, Rat NUDT15 Polyclonal Antibody | anti-NUDT15 antibody
NUDT15 Polyclonal Antibody
IHC: 1:100-1:200
Western Blot (WB)
(Western Blot of analysis of extracts of rat spleen, using NUDT15 at 1:1000 dilution.)
Western Blot (WB)
(Western Blot of analysis of extracts of rat spleen, using NUDT15 at 1:1000 dilution.)
NCBI and Uniprot Product Information
Uniprot Description
NUDT15: Mediates the hydrolysis of some nucleoside diphosphate derivatives. Can degrade 8-oxo-dGTP in vitro, suggesting that it may remove an oxidatively damaged form of guanine (7,8-dihydro-8- oxoguanine) from DNA and the nucleotide pool, thereby preventing misincorporation of 8-oxo-dGTP into DNA thus preventing A:T to C:G transversions. Its substrate specificity in vivo however remains unclear. May have a role in DNA synthesis and cell cycle progression through the interaction with PCNA. Belongs to the Nudix hydrolase family.
Protein type: EC 3.6.1.55; Hydrolase
Chromosomal Location of Human Ortholog: 13q14.2
Cellular Component: cytosol
Molecular Function: 8-oxo-7,8-dihydroguanine triphosphatase activity; metal ion binding; nucleoside-diphosphatase activity; nucleoside-triphosphate diphosphatase activity; protein binding
Biological Process: dGTP catabolic process; DNA protection; exogenous drug catabolic process; mitotic cell cycle; purine nucleotide catabolic process
Disease: Thiopurines, Poor Metabolism Of, 2
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Product Notes
The NUDT15 nudt15 (Catalog #AAA9432037) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NUDT15 Polyclonal Antibody reacts with Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's NUDT15 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). WB: 1:500-1:2000 IHC: 1:100-1:200. Researchers should empirically determine the suitability of the NUDT15 nudt15 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NUDT15, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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