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Western Blot (WB) (Mouse Cckar Antibody (C-term) western blot analysis in mouse bladder,cerebellum and lung tissue lysates (35ug/lane).This demonstrates the Mouse Cckar antibody detected the Mouse Cckar protein (arrow).)

Rabbit M Cckar Polyclonal Antibody | anti-Cckar antibody

M Cckar Antibody (C-term)

Gene Names
Cckar; AW106902
Reactivity
Mouse (Predicted Reactivity: Rat)
Applications
Western Blot, ELISA
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
M Cckar; Polyclonal Antibody; M Cckar Antibody (C-term); Cholecystokinin receptor type A; CCK-A receptor; CCK-AR; Cholecystokinin-1 receptor; CCK1-R; Cckar; anti-Cckar antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Mouse (Predicted Reactivity: Rat)
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This Mouse Cckar antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 325-356 amino acids from the C-terminal region of mouse Cckar.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.43 (varies by lot)
Sequence Positions
325-356
Sequence Length
436
Applicable Applications for anti-Cckar antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Crown Antibody
Yes
Antigen Source
Mouse
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(Mouse Cckar Antibody (C-term) western blot analysis in mouse bladder,cerebellum and lung tissue lysates (35ug/lane).This demonstrates the Mouse Cckar antibody detected the Mouse Cckar protein (arrow).)

Western Blot (WB) (Mouse Cckar Antibody (C-term) western blot analysis in mouse bladder,cerebellum and lung tissue lysates (35ug/lane).This demonstrates the Mouse Cckar antibody detected the Mouse Cckar protein (arrow).)
Related Product Information for anti-Cckar antibody
Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity).
Product Categories/Family for anti-Cckar antibody
References
Takata Y., et al. Gene 187:267-271(1997).
Lacourse K.A., et al. Biochem. Biophys. Res. Commun. 236:630-635(1997).
Carninci P., et al. Science 309:1559-1563(2005).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
48437
NCBI Official Full Name
cholecystokinin receptor type A
NCBI Official Synonym Full Names
cholecystokinin A receptor
NCBI Official Symbol
Cckar
NCBI Official Synonym Symbols
AW106902
NCBI Protein Information
cholecystokinin receptor type A
UniProt Protein Name
Cholecystokinin receptor type A
Protein Family
UniProt Gene Name
Cckar
UniProt Synonym Gene Names
CCK-A receptor; CCK-AR; CCK1-R
UniProt Entry Name
CCKAR_MOUSE

Uniprot Description

CCKAR: Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family.

Protein type: Membrane protein, integral; Receptor, GPCR; GPCR, family 1; Membrane protein, multi-pass

Cellular Component: membrane; integral to plasma membrane; endoplasmic reticulum; lysosome; cytoplasm; plasma membrane; integral to membrane; terminal button; cytosol; endosome

Molecular Function: G-protein coupled receptor activity; signal transducer activity; cholecystokinin receptor activity; peptide binding

Biological Process: gastric acid secretion; eating behavior; regulation of potassium ion transport; neuron migration; regulation of hormone secretion; thermoregulation; regulation of calcium ion transport; pancreatic juice secretion; signal transduction; reduction of food intake in response to dietary excess; cellular response to hormone stimulus; response to starvation; G-protein coupled receptor protein signaling pathway; elevation of cytosolic calcium ion concentration; axonogenesis; response to heat; insulin secretion; actin cytoskeleton reorganization; forebrain development; digestion; feeding behavior

Research Articles on Cckar

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Product Notes

The Cckar cckar (Catalog #AAA9212671) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 325-356. The M Cckar Antibody (C-term) reacts with Mouse (Predicted Reactivity: Rat) and may cross-react with other species as described in the data sheet. AAA Biotech's M Cckar can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the Cckar cckar for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "M Cckar, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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