Neuropeptide Y Receptor Y2 Assay System | NPY2R assay system
Neuropeptide Y Receptor Y2 (NPY2R) ACTOne Stable Cell Line
NCBI and Uniprot Product Information
Uniprot Description
NPY2R: Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is PYY > NPY > PYY (3-36) > NPY (2-36) > [Ile-31, Gln-34] PP > [Leu- 31, Pro-34] NPY > PP, [Pro-34] PYY and NPY free acid. Belongs to the G-protein coupled receptor 1 family.
Protein type: Membrane protein, multi-pass; GPCR, family 1; Receptor, GPCR; Membrane protein, integral
Chromosomal Location of Human Ortholog: 4q31
Cellular Component: nonmotile primary cilium; integral to plasma membrane; plasma membrane
Molecular Function: peptide YY receptor activity; protein binding; calcium channel regulator activity; neuropeptide Y receptor activity; receptor activity
Biological Process: positive regulation of dopamine secretion; secretion; positive regulation of cell adhesion; behavioral fear response; negative regulation of synaptic transmission, glutamatergic; positive regulation of peptide secretion; locomotory behavior; negative regulation of cAMP biosynthetic process; elevation of cytosolic calcium ion concentration; neuropeptide signaling pathway; negative regulation of secretion; positive regulation of smooth muscle contraction; G-protein signaling, adenylate cyclase inhibiting pathway; regulation of sensory perception of pain; negative regulation of neurological process; nitric oxide mediated signal transduction; positive regulation of circadian sleep/wake cycle, non-REM sleep
Research Articles on NPY2R
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Product Notes
The NPY2R npy2r (Catalog #AAA433634) is an Assay System and is intended for research purposes only. The product is available for immediate purchase. cAMP dependent assay for Gi-coupled human NPY2R; cell-based high-throughput screening of human NPY2 inhibitors. Researchers should empirically determine the suitability of the NPY2R npy2r for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Neuropeptide Y Receptor Y2, Assay System" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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