Typical Testing Data/Standard Curve (for reference only)
Human NPYR2 (Neuropeptide Y Receptor Y2) CLIA Kit | NPYR2 clia kit
Human NPYR2 (Neuropeptide Y Receptor Y2) CLIA Kit
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
Principle of the Assay: This kit uses Sandwich-CLIA as the method. The micro CLIA plate provided in this kit has been pre-coated with an antibody specific to NPYR2. Standards or samples are added to the appropriate micro CLIA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for NPYR2 and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain NPYR2, biotinylated detection antibody and Avidin-HRP conjugate will appear fluorescence. The Relative light unit (RLU) value is measured spectrophotometrically by the Chemiluminescence immunoassay analyzer. The RLU value is positively associated with the concentration of NPYR2. You can calculate the concentration of NPYR2 in the samples by comparing the RLU value of the samples to the standard curve.
NCBI and Uniprot Product Information
Uniprot Description
NPY2R: Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is PYY > NPY > PYY (3-36) > NPY (2-36) > [Ile-31, Gln-34] PP > [Leu- 31, Pro-34] NPY > PP, [Pro-34] PYY and NPY free acid. Belongs to the G-protein coupled receptor 1 family.
Protein type: GPCR, family 1; Membrane protein, integral; Receptor, GPCR; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 4q31
Cellular Component: nonmotile primary cilium; integral to plasma membrane; plasma membrane; cytosol
Molecular Function: peptide YY receptor activity; protein binding; calcium channel regulator activity; neuropeptide Y receptor activity; receptor activity
Biological Process: positive regulation of dopamine secretion; secretion; behavioral fear response; negative regulation of synaptic transmission, glutamatergic; positive regulation of peptide secretion; locomotory behavior; synaptic transmission; negative regulation of cAMP biosynthetic process; elevation of cytosolic calcium ion concentration; cell surface receptor linked signal transduction; neuropeptide signaling pathway; negative regulation of secretion; feeding behavior; regulation of sensory perception of pain; positive regulation of smooth muscle contraction; G-protein signaling, adenylate cyclase inhibiting pathway; nitric oxide mediated signal transduction; negative regulation of neurological process; positive regulation of circadian sleep/wake cycle, non-REM sleep
Research Articles on NPYR2
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Product Notes
The Human NPYR2 npy2r (Catalog #AAA2530805) is a CLIA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2530805 CLIA Kit recognizes Human NPYR2. It is sometimes possible for the material contained within the vial of "NPYR2 (Neuropeptide Y Receptor Y2), CLIA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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