Mouse anti-Human Tumor Type M2 Pyruvate Kinase Monoclonal Antibody | anti-PKM2 antibody
Mouse Anti Human Tumor Type M2 Pyruvate Kinase, Clone PAT1B10AT
Gene Names
TRIM35; HLS5; MAIR
Reactivity
Human
Applications
ELISA, Immunofluorescence, Western Blot
Purity
Purified from mouse ascitic fluids by protein-A affinity chromatography
Synonyms
Tumor Type M2 Pyruvate Kinase; Monoclonal Antibody; Mouse Anti Human Tumor Type M2 Pyruvate Kinase; Clone PAT1B10AT; PKM2 PAT1B10AT Antibody; Mouse Anti Human; Pyruvate kinase isozymes M1/M2; EC 2.7.1.40; Pyruvate kinase muscle isozyme; Pyruvate kinase 2/3; Cytosolic thyroid hormone-binding protein; CTHBP; THBP1; M2PK; PKM2; PK3; PK2; PKM; TCB; OIP3; MGC3932; anti-PKM2 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Clone Number
PAT1B10AT
Purity/Purification
Purified from mouse ascitic fluids by protein-A affinity chromatography
Form/Format
1mg/ml containing PBS, pH-7.4, 10% Glycerol and 0.02% Sodium Azide.
Sterile filtered colorless solution.
Sterile filtered colorless solution.
Sequence Length
266
Applicable Applications for anti-PKM2 antibody
ELISA (EIA), Western Blot (WB) Immunofluorescence (IF)
Application Notes
PKM2 antibody has been tested by ELISA, Western blot analysis and Immunofluorescence analysis to assure specificity and reactivity.
Ig Subclass
Mouse IgG1 heavy chain and k light chain.
Immunogen
Anti-human PKM2 mAb, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human PKM2 protein 1-531 amino acids purified from E Coli.
Preparation and Storage
Storage: For periods up to 1 month store at 4 degree C, for longer periods of time, store at -20 degree C. Prevent freeze thaw cycles.
Stability: 12 months at -20 degree C. 1 month at 4 degree C.
Stability: 12 months at -20 degree C. 1 month at 4 degree C.
Related Product Information for anti-PKM2 antibody
Pyruvate kinase is a key enzyme in the glycolytic pathway. The M2 isoenzyme of pyruvate kinase is specifically expressed at high levels in tumor cells, and can be measured in plasma of patients with advanced breast cancer. The marker is useful for measuring disease activity, sensitivity to chemotherapy and recurrence.
Product Categories/Family for anti-PKM2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
55,914 Da
NCBI Official Full Name
tripartite motif-containing protein 35 isoform 2
NCBI Official Synonym Full Names
tripartite motif containing 35
NCBI Official Symbol
TRIM35
NCBI Official Synonym Symbols
HLS5; MAIR
NCBI Protein Information
tripartite motif-containing protein 35
UniProt Protein Name
Tripartite motif-containing protein 35
UniProt Gene Name
TRIM35
UniProt Synonym Gene Names
HLS5; KIAA1098
UniProt Entry Name
TRI35_HUMAN
Uniprot Description
TRIM35: May play a role as a tumor suppressor. Implicated in the cell death mechanism. Belongs to the TRIM/RBCC family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Ubiquitin conjugating system
Chromosomal Location of Human Ortholog: 8p21.2
Cellular Component: cytoplasm; nucleus
Biological Process: apoptosis; innate immune response; negative regulation of mitotic cell cycle; positive regulation of apoptosis
Similar Products
Product Notes
The PKM2 trim35 (Catalog #AAA140517) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Mouse Anti Human Tumor Type M2 Pyruvate Kinase, Clone PAT1B10AT reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Tumor Type M2 Pyruvate Kinase can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB) Immunofluorescence (IF). PKM2 antibody has been tested by ELISA, Western blot analysis and Immunofluorescence analysis to assure specificity and reactivity. Researchers should empirically determine the suitability of the PKM2 trim35 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Tumor Type M2 Pyruvate Kinase, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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