Western Blot (WB)
(Western blot of rat cortex lysate showing specific immunolabeling of ~ 36k syntaxin 1A protein)
Mouse STX1A Monoclonal Antibody | anti-STX1A antibody
STX1A antibody
Gene Names
STX1A; STX1; HPC-1; P35-1; SYN1A
Applications
Western Blot, Immunohistochemistry
Purity
STX1A antibody was purified by Protein G affinity chromatography
Synonyms
STX1A; Monoclonal Antibody; STX1A antibody; Monoclonal STX1A; Anti-STX1A; STX 1A; STX-1A; Syntaxin 1A brain; HPC-1; STX1; p35-1; Syntaxin; anti-STX1A antibody
Host
Mouse
Clonality
Monoclonal
Isotype
IgG1
Clone Number
SP8
Purity/Purification
STX1A antibody was purified by Protein G affinity chromatography
Form/Format
Supplied in liquid form in 10 mM HEPES buffer (pH 7.5), 150 mM NaCl, 100 ug per ml BSA and 50% glycerol
Sequence Length
288
Applicable Applications for anti-STX1A antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
WB: 1:1000
IHC: 1:100
IHC: 1:100
Biological Significance
STX1A vesicles store neurotransmitters that are released during calcium-regulated exocytosis. The specificity of neurotransmitter release requires the localization of both synaptic vesicles and calcium channels to the presynaptic active zone. Syntaxins function in this vesicle fusion process. Syntaxins also serve as a substrate for botulinum neurotoxin type C, a metalloprotease that blocks exocytosis and has high affinity for a molecular complex that includes the alpha-latrotoxin receptor which produces explosive exocytosis.
Western Blot (WB)
(Western blot of rat cortex lysate showing specific immunolabeling of ~ 36k syntaxin 1A protein)
Western Blot (WB)
(Western blot of rat cortex lysate showing specific immunolabeling of ~ 36k syntaxin 1A protein)
Related Product Information for anti-STX1A antibody
Mouse monoclonal STX1A antibody
Product Categories/Family for anti-STX1A antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
33,023 Da
NCBI Official Full Name
STX1A
NCBI Official Synonym Full Names
syntaxin 1A (brain)
NCBI Official Symbol
STX1A
NCBI Official Synonym Symbols
STX1; HPC-1; P35-1; SYN1A
NCBI Protein Information
syntaxin-1A
UniProt Protein Name
Putative uncharacterized protein STX1A
Protein Family
UniProt Gene Name
STX1A
UniProt Entry Name
Q75ME0_HUMAN
NCBI Description
This gene encodes a member of the syntaxin superfamily. Syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane. Syntaxins possess a single C-terminal transmembrane domain, a SNARE [Soluble NSF (N-ethylmaleimide-sensitive fusion protein)-Attachment protein REceptor] domain (known as H3), and an N-terminal regulatory domain (Habc). Syntaxins bind synaptotagmin in a calcium-dependent fashion and interact with voltage dependent calcium and potassium channels via the C-terminal H3 domain. This gene product is a key molecule in ion channel regulation and synaptic exocytosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]
Research Articles on STX1A
Similar Products
Product Notes
The STX1A stx1a (Catalog #AAA838380) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's STX1A can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). WB: 1:1000 IHC: 1:100. Researchers should empirically determine the suitability of the STX1A stx1a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "STX1A, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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