Western Blot (WB)
(Western blot analysis of PD-1 in transfected 293 cell lysate with PD-1 antibody at (A) 0.5 and (B) 1 μg/mL.)
Mouse anti-Human PD-1 Monoclonal Antibody | anti-PDCD1 antibody
PD-1 Antibody [8A4]
Immunohistochemistry starting at 5 mug/mL.
As with all antibodies care should be taken to avoid repeated freeze thaw cycles
Antibodies should not be exposed to prolonged high temperatures.
Western Blot (WB)
(Western blot analysis of PD-1 in transfected 293 cell lysate with PD-1 antibody at (A) 0.5 and (B) 1 μg/mL.)
Western Blot (WB)
(Western blot analysis of PD-1 in transfected 293 cell lysate with PD-1 antibody at (A) 0.5 and (B) 1 μg/mL.)
Immunohistochemistry (IHC)
(Immunohistochemistry of PD-1 in (A) human tonsil tissue, (B) human lymph node tissue, and (C) human spleen tissue with PD-1 antibody at 5 μg/mL. (D) Immunohistochemistry in human tonsil tissue with control mouse IgG staining at 5 μg/mL.)
Immunohistochemistry (IHC)
(Immunohistochemistry of PD-1 in (A) human tonsil tissue, (B) human lymph node tissue, and (C) human spleen tissue with PD-1 antibody at 5 μg/mL. (D) Immunohistochemistry in human tonsil tissue with control mouse IgG staining at 5 μg/mL.)
Immunohistochemistry (IHC)
(Immunohistochemistry of PD-1 in (A) human breast cancer tissue and (B) human normal breast tissue with PD-1 antibody at 5 μg/mL.)
Immunohistochemistry (IHC)
(Immunohistochemistry of PD-1 in (A) human breast cancer tissue and (B) human normal breast tissue with PD-1 antibody at 5 μg/mL.)
Immunocytochemistry (ICC)
(Immunocytochemistry of PD-1 in transfected 293 cells with PD-1 antibody at 5 μg/mL. Lower left: Immunocytochemistry in transfected 293 cells with control mouse IgG antibody at 5 μg/mL.)
Immunocytochemistry (ICC)
(Immunocytochemistry of PD-1 in transfected 293 cells with PD-1 antibody at 5 μg/mL. Lower left: Immunocytochemistry in transfected 293 cells with control mouse IgG antibody at 5 μg/mL.)
Immunofluorescence (IF)
(Immunofluorescence of PD-1 in transfected 293 cells with PD-1 antibody at 5 μg/mL. Lower left: Immunofluorescence in transfected 293 cells with control mouse IgG antibody at 5 μg/mL.Red: PD1 Antibody [8A4]Blue: DAPI staining)
Immunofluorescence (IF)
(Immunofluorescence of PD-1 in transfected 293 cells with PD-1 antibody at 5 μg/mL. Lower left: Immunofluorescence in transfected 293 cells with control mouse IgG antibody at 5 μg/mL.Red: PD1 Antibody [8A4]Blue: DAPI staining)
Western Blot (WB)
(Western blot analysis of PD-1 in overexpressing 293 cells using antibody at 1, 0.5, and 0.25 μg/ml, respectively.)
Western Blot (WB)
(Western blot analysis of PD-1 in overexpressing 293 cells using antibody at 1, 0.5, and 0.25 μg/ml, respectively.)
ELISA (EIA)
(Titration curve analysis of PD-1 mAbs to detect recombinant PD-1 in ELISA abs at decreasing concentrations.)
ELISA (EIA)
(Titration curve analysis of PD-1 mAbs to detect recombinant PD-1 in ELISA abs at decreasing concentrations.)
NCBI and Uniprot Product Information
Observed: 38 kDa
NCBI Description
This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. [provided by RefSeq, Jul 2008]
Uniprot Description
PDCD1: a single-pass type I membrane protein. A negative regulator of activated T cells, is upregulated in human and mouse 'exhausted' T cells during persistent viral infection. A marker of angioimmunoblastic T-cell lymphoma and germinal center associated T cells.
Protein type: Apoptosis; Membrane protein, integral
Chromosomal Location of Human Ortholog: 2q37.3
Cellular Component: plasma membrane
Molecular Function: protein binding; signal transducer activity
Biological Process: humoral immune response; multicellular organismal development; T cell costimulation
Disease: Systemic Lupus Erythematosus
Research Articles on PDCD1
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Product Notes
The PDCD1 pdcd1 (Catalog #AAA154529) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The PD-1 Antibody [8A4] reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PD-1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Immunocytochemistry (ICC), Immunofluorescence (IF). Western blot at 0.5 - 1 mug/mL Immunohistochemistry starting at 5 mug/mL.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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