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Western Blot (WB) (Western blot analysis of PD-1 in A-20 cell lysate with PD-1 antibody at 1 ug/mL in the (A) absence and (B) presence of blocking recombinant protein.)

Mouse PD-1 Monoclonal Antibody | anti-PD-1 antibody

PD-1 Monoclonal Antibody

Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Immunoaffinity chromotography purified IgG
Synonyms
PD-1; Monoclonal Antibody; PD-1 Monoclonal Antibody; PD-1 (7A11B1); Programmed cell death 1; PDCD-1; CD279; anti-PD-1 antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Clone Number
7A11B1
Purity/Purification
Immunoaffinity chromotography purified IgG
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Applicable Applications for anti-PD-1 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Immunogen Type
Recombinant protein
Immunogen Description
A ~150 amino acid recombinant protein from near the terminus terminus of mouse PD-1.
Target Name
PD-1
Preparation and Storage
Can be stored at -20 degree C, stable for one year.

Western Blot (WB)

(Western blot analysis of PD-1 in A-20 cell lysate with PD-1 antibody at 1 ug/mL in the (A) absence and (B) presence of blocking recombinant protein.)

Western Blot (WB) (Western blot analysis of PD-1 in A-20 cell lysate with PD-1 antibody at 1 ug/mL in the (A) absence and (B) presence of blocking recombinant protein.)

Immunohistochemistry (IHC)

(Immunohistochemistry of PD-1 in mouse brain tissue with PD-1 antibody at 2.5 ug/mL.)

Immunohistochemistry (IHC) (Immunohistochemistry of PD-1 in mouse brain tissue with PD-1 antibody at 2.5 ug/mL.)
Related Product Information for anti-PD-1 antibody
Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by cognate peptides bound to MHC molecules on antig en-presenting cells (APC). T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC. PD-1 can bind two different but related ligands, PDL-1 and PDL-2. Upon binding to either of these ligands, signals generated by PD-1 inhibit the activation of the immune response in the absence of "danger signals" such as LPS or other molecules associated with bacteria or other pathogens. Evidence for this is seen in PD1-null mice who exhibit hyperactivated immune systems and autoimmune diseases. Despite its predicted molecular weight, PD-1 often migrates at higher molecular weight in SDS-PAGE.
Product Categories/Family for anti-PD-1 antibody

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Product Notes

The PD-1 (Catalog #AAA9400187) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The PD-1 Monoclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's PD-1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the PD-1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PD-1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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