CD208 (LAMP3) Recombinant Protein | CD208 recombinant protein
Human CD208 Recombinant (LAMP3)
Purity
>95%, as determined by SDS-PAGE and HPLC
Synonyms
CD208 (LAMP3); Human CD208 Recombinant (LAMP3); Human CD208 Recombinant (LAMP3) ; CD208; DC-LAMP; DCLAMP; LAMP; TSC403 LAMP3; CD208 recombinant protein
Host
HEk293 Cells
Purity/Purification
>95%, as determined by SDS-PAGE and HPLC
Form/Format
Recombinant CD208 is supplied as a 0.2 um filtered PBS solution, pH7.2.
Sequence Length
416
Domain
Ig-like C2
Host Note
Optimized DNA sequence encoding Human extracellular domain of human CD208 including a C-terminal 6His tag was expressed in HEK293 cells.
Endotoxin
Endotoxin content was assayed using a LAL gel clot method.
Endotoxin level was found to be less than 0.1 ng/ug (1EU/ug).
Endotoxin level was found to be less than 0.1 ng/ug (1EU/ug).
Molecular Weight Note
Recombinant CD208 is a monomer protein consisting of 365 amino acid residue subunits, due to glycosylation migrates as an approximately 70-90 kDa protein on SDS-PAGE.
Preparation and Storage
Recombinant CD208, as supplied, can be stored in working aliquots at 2 degree - 8 degree C for one month, or at -20 degree C to -70 degree C for twelve months.
Avoid repeated freeze/thaw cycles.
Avoid repeated freeze/thaw cycles.
Related Product Information for CD208 recombinant protein
LAMP3 is a member of the LAMP family. LAMP1 and LAMP2 are located primarily in the lysosomal membrane and are rarely present on the surface of normal cells. They are the major carriers for poly-N- acetyllactosamines, including those with sialyl- Lex termini, which are critical ligands for the E- selectin present on endothelial cells and platelets. Cancer cells show increased levels of sialyl-Lex determinants and adhere to vascular endothelial cells through their interaction with E- selectin.
Product Categories/Family for CD208 recombinant protein
References
• depletion of alveolar glycogen corresponds with immunohistochemical development of CD208 antigen expression in perinatal lamb lung .J. Histochem. Cytochem., Nov 2006; 54: 1247 - 1253.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
44,346 Da
NCBI Official Full Name
lysosome-associated membrane glycoprotein 3
UniProt Protein Name
Lysosome-associated membrane glycoprotein 3
UniProt Gene Name
LAMP3
UniProt Synonym Gene Names
DCLAMP; TSC403; LAMP-3; Lysosomal-associated membrane protein 3; DC LAMP
UniProt Entry Name
LAMP3_HUMAN
NCBI Description
Dendritic cells (DCs) are the most potent antigen-presenting cells. Immature DCs efficiently capture antigens and differentiate into interdigitating dendritic cells (IDCs) in lymphoid tissues that induce primary T-cell responses (summary by de Saint-Vis et al., 1998 [PubMed 9768752]).[supplied by OMIM, Dec 2010]
Uniprot Description
LAMP3: Might change the lysosome function after the transfer of peptide-MHC class II molecules to the surface of dendritic cells. Belongs to the LAMP family.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 3q26.3-q27
Cellular Component: lysosomal membrane; integral to membrane
Biological Process: cell proliferation; immune system process
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Product Notes
The CD208 lamp3 (Catalog #AAA553150) is a Recombinant Protein produced from HEk293 Cells and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "CD208 (LAMP3), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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