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Western Blot (WB) (Western blot analysis of TSLP Receptor in mouse heart tissue lysate with TSLP Receptor antibody at 1 ug/mL in (A) the presence and (B) the absence of blocking peptide.)

Rabbit anti-Mouse TSLP Polyclonal Antibody | anti-TSLP antibody

TSLP Receptor Antibody

Gene Names
Crlf2; CRLM2; Ly114; Tpte2; Tslpr
Reactivity
Mouse
Applications
ELISA, Western Blot
Purity
Affinity chromatography purified via peptide column
Synonyms
TSLP; Polyclonal Antibody; TSLP Receptor Antibody; TSLP Receptor; Mouse thymic stromal lymphopoietin receptor; TSLP-R; anti-TSLP antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Mouse
Clonality
Polyclonal
Purity/Purification
Affinity chromatography purified via peptide column
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
359
Applicable Applications for anti-TSLP antibody
ELISA (EIA), Western Blot (WB)
Immunogen Type
Peptide
Immunogen Description
Raised against a 21 amino acid peptide from near the center of mouse TSLP receptor.
Target Name
TSLP Receptor
Preparation and Storage
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Western Blot (WB)

(Western blot analysis of TSLP Receptor in mouse heart tissue lysate with TSLP Receptor antibody at 1 ug/mL in (A) the presence and (B) the absence of blocking peptide.)

Western Blot (WB) (Western blot analysis of TSLP Receptor in mouse heart tissue lysate with TSLP Receptor antibody at 1 ug/mL in (A) the presence and (B) the absence of blocking peptide.)
Related Product Information for anti-TSLP antibody
Thymic stromal lymphopoietin (TSLP) has recently been identified as an important factor capable of driving dendritic cell maturation and activation. It is involved in the positive selection of regulatory T cells, maintenance of peripheral CD4+ T cell homeostasis and the induction of CD4+ T cell-mediated allergic reaction. TSLP is also capable of supporting the growth of fetal liver and adult B cell progenitors and their differentiation to the IgM-positive stage of B cell development. Its receptor TSLP-R will bind TSLP in a low-affinity fashion in transfected cells; co-transfection with IL-7R-alpha cDNA results in high-affinity binding and a functional heteromeric complex. This heteromeric receptor requires stat5 for TSLP-mediated signal transduction and is inhibited by SOCS-1. The approximately 75 kDa band seen in the immunoblot may be a post-translationally modified form of TSLP-R.
Product Categories/Family for anti-TSLP antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
13,236 Da
NCBI Official Full Name
cytokine receptor-like factor 2 isoform 2
NCBI Official Synonym Full Names
cytokine receptor-like factor 2
NCBI Official Symbol
Crlf2
NCBI Official Synonym Symbols
CRLM2; Ly114; Tpte2; Tslpr
NCBI Protein Information
cytokine receptor-like factor 2
UniProt Protein Name
Cytokine receptor-like factor 2
UniProt Gene Name
Crlf2
UniProt Synonym Gene Names
Crlm2; Tpte2; Tslpr; CRLM-2; TSLP receptor
UniProt Entry Name
CRLF2_MOUSE

Uniprot Description

CRLF2: Receptor for thymic stromal lymphopoietin (TSLP). Forms a functional complex with TSLP and IL7R which is capable of stimulating cell proliferation through activation of STAT3 and STAT5. Also activates JAK2. Implicated in the development of the hematopoietic system. Belongs to the type I cytokine receptor family. Type 5 subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Cellular Component: membrane; cell; plasma membrane; integral to membrane; extracellular region

Molecular Function: cytokine activity

Biological Process: immunoglobulin secretion during immune response; inflammatory response

Research Articles on TSLP

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Product Notes

The TSLP crlf2 (Catalog #AAA9414366) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TSLP Receptor Antibody reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's TSLP can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). Researchers should empirically determine the suitability of the TSLP crlf2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TSLP, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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