Structure
SB 202190, Inhibitor
SB 202190
Purity
>98% (HPLC)
Synonyms
SB 202190; SB202190; SB-202190; inhibitor
Purity/Purification
>98% (HPLC)
Suitability
DMSO: >=40mg/mL
Target
p38 MAPK
Receptor
p38alpha; p38beta
Chemical Name
Phenol, 4-[4-(4-fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-2-yl]
SMILES
OC1=CC=C(C2=NC(C3=CC=C(F)C=C3)=C(C4=CC=NC=C4)N2)C=C1
Molecular Formula
C20H14FN3O
CAS Number
152121-30-7
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Stability: >=2 years
Shipping: Ice Pack
Structure
Structure
Related Product Information for SB 202190, inhibitor
SB 202190 (SB202190, SB-202190) is a potent inhibitor p38alpha and p38beta with IC50 of 50nM and 100nM respectively; stimulates the activity of CPP32-like caspases, potentiates apoptosis induced by Fas (APO-1) ligation or UV irradiation.
Product Categories/Family for SB 202190, inhibitor
References
1. Davies SP, et al. Biochem J. 2000 Oct 1; 351 (Pt 1):95-105.
2. Nemoto S, et al. J Biol Chem. 1998 Jun 26; 273 (26):16415-20.
3. Manthey CL, et al. J Leukoc Biol. 1998 Sep; 64 (3):409-17.
2. Nemoto S, et al. J Biol Chem. 1998 Jun 26; 273 (26):16415-20.
3. Manthey CL, et al. J Leukoc Biol. 1998 Sep; 64 (3):409-17.
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Product Notes
The SB 202190 (Catalog #AAA3602123) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "SB 202190, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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