Structure
Revaprazan hydrochloride, Inhibitor
Revaprazan hydrochloride
Purity
>98% (HPLC)
Synonyms
Revaprazan hydrochloride; SB-641257; YH-1885; inhibitor
Purity/Purification
>98% (HPLC)
Suitability
DMSO: 10mM (<1mg/mL refers to the product slightly soluble or insoluble)
Target
Proton Pump
Receptor
H+/K+-ATPase
Chemical Name
N-(4-fluorophenyl)-4, 5-dimethyl-6-(1-methyl-3, 4-dihydro-1H-isoquinolin-2-yl)pyrimidin-2-amine hydrochloride
SMILES
Cl.CC1N(CCc2ccccc12)c3nc(Nc4ccc(F)cc4)nc(C)c3C
Molecular Formula
C22H24ClFN4
CAS Number
178307-42-1
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Stability: >=2 years
Shipping: Ice Pack
Structure
Structure
Related Product Information for Revaprazan hydrochloride, inhibitor
Revaprazan (SB-641257; YH-1885) potent potassium-competitive acid blocker (P-CAB) that inhibits H+, K+-ATPase in a reversible and K+-competitive manner; reduces gastric acid secretion, also exerts anti-inflammatory action against Helicobacter pylori-induced COX-2 expression by inactivating Akt signaling. Ulcer Approved
Product Categories/Family for Revaprazan hydrochloride, inhibitor
References
1. Li H, et al. Drug Metab Dispos. 2001 Jan; 29 (1):54-9.
2. Lee JS, et al. J Clin Biochem Nutr. 2012 Sep; 51 (2):77-83.
3. Inatomi N, et al. Pharmacol Ther. 2016 Dec; 168:12-22.
2. Lee JS, et al. J Clin Biochem Nutr. 2012 Sep; 51 (2):77-83.
3. Inatomi N, et al. Pharmacol Ther. 2016 Dec; 168:12-22.
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Product Notes
The Revaprazan hydrochloride (Catalog #AAA3602683) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Revaprazan hydrochloride, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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