Structure
AZD-0865 Biochemical
AZD-0865
Purity
>98% (HPLC)
Synonyms
AZD-0865; Linaprazan; AZD0865; AZD 0865; AZD-0865 biochemical
Purity/Purification
>98% (HPLC)
Suitability
DMSO: >=35mg/mL
Target
Proton Pump
Receptor
Proton Pump
Chemical Name
Imidazo[1, 2-a]pyridine-6-carboxamide, 8-[[(2, 6-dimethylphenyl)methyl]amino]-N-(2-hydroxyethyl)-2, 3-dimethyl
SMILES
CC1=C(C(=CC=C1)C)CNC2=CC(=CN3C2=NC(=C3C)C)C(=O)NCCO
Molecular Formula
C21H26N4O2
CAS Number
248919-64-4
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Stability: >=2 years
Shipping: Ice Pack
Structure
Structure
Related Product Information for AZD-0865 biochemical
A potent, selective acid pump antagonist (potassium-competitive acid blocker or P-CAB) that reversiblely inhibits gastric H+/K+-ATPase with pIC50 of 6.5; inhibits H+/K+-ATPase activity in a K (+)-competitive manner with Ki of 46nM, shows no ativity for porcine renal Na (+), K (+)-ATPase at 100uM; inhibits gastric acid secretion in vivo. UlcerPhase 2 Discontinued
Product Categories/Family for AZD-0865 biochemical
References
1. Bailey N, et al. Bioorg Med Chem Lett. 2009 Jul 1; 19 (13):3602-6.
2. Gedda K, et al. Biochem Pharmacol. 2007 Jan 15; 73 (2):198-205.
3. Kirchhoff P, et al. Am J Physiol Gastrointest Liver Physiol. 2006 Nov; 291 (5):G838-43.
2. Gedda K, et al. Biochem Pharmacol. 2007 Jan 15; 73 (2):198-205.
3. Kirchhoff P, et al. Am J Physiol Gastrointest Liver Physiol. 2006 Nov; 291 (5):G838-43.
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Product Notes
The AZD-0865 (Catalog #AAA3603728) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "AZD-0865, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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