PDCD10 Antibody | anti-PDCD10 antibody

PDCD10 Antibody

Cat. Num. AAA8516522

• Gene Names: PDCD10; CCM3; TFAR15
• Reactivity: Human, Mouse, Rat
• Applications: Western Blot, Immunohistochemistry
• Purity: Immunogen affinity purified
• Synonyms: PDCD10; PDCD10 Antibody; CCM3; MGC1212; MGC24477; TFAR15; anti-PDCD10 antibody

• Reactivity: Human, Mouse, Rat
• Specificity: PDCD10 Antibody detects endogenous levels of total PDCD10
• Purity/Purification: Immunogen affinity purified
• Form/Format: In phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Sequence Length: 212

• Applicable Applications for anti-PDCD10 antibody: Western Blot (WB), Immunohistochemistry (IHC)
• Application Notes: WB: 1:500-1:1000; IHC: 1:50-1:100
• Immunogen: Fusion protein of human PDCD10
• Preparation and Storage: Store at-20 degree C for 1 year

Western Blot (WB)

(Western blot analysis of extracts of various celllines, using PDCD10antibody|Immunohistochemistry of paraffin-embeddedhuman renal cancer tissue using PDCD10antibody.)

Related Product Information for anti-PDCD10 antibody

This gene encodes an evolutionarily conserved protein associated with cell apoptosis. The protein interacts with the serine/threonine protein kinase MST4 to modulate the extracellular signal-regulated kinase (ERK) pathway. It also interacts with and is phosphoryated by serine/threonine kinase 25, and is thought to function in a signaling pathway essential for vascular developent. Mutations in this gene are one cause of cerebral cavernous malformations, which are vascular malformations that cause seizures and cerebral hemorrhages. Multiple alternatively spliced variants, encoding the same protein, have been identified.

NCBI and Uniprot Product Information

• NCBI GI #: 20127517
• NCBI GeneID: 11235
• NCBI Accession #: NP_009148.2
• NCBI GenBank Nucleotide #: NM_007217.3
• UniProt Accession #: Q9BUL8; O14811; A8K515; D3DNN5
• Molecular Weight: 25kDa
• NCBI Official Full Name: programmed cell death protein 10
• NCBI Official Synonym Full Names: programmed cell death 10
• NCBI Official Symbol: PDCD10
• NCBI Official Synonym Symbols: CCM3; TFAR15
• NCBI Protein Information: programmed cell death protein 10
• UniProt Protein Name: Programmed cell death protein 10
• Protein Family: Programmed cell death protein
• UniProt Gene Name: PDCD10
• UniProt Synonym Gene Names: CCM3; TFAR15

NCBI Description

This gene encodes an evolutionarily conserved protein associated with cell apoptosis. The protein interacts with the serine/threonine protein kinase MST4 to modulate the extracellular signal-regulated kinase (ERK) pathway. It also interacts with and is phosphoryated by serine/threonine kinase 25, and is thought to function in a signaling pathway essential for vascular developent. Mutations in this gene are one cause of cerebral cavernous malformations, which are vascular malformations that cause seizures and cerebral hemorrhages. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]

Uniprot Description

Promotes cell proliferation. Modulates apoptotic pathways. Increases mitogen-activated protein kinase activity and STK26 activity (PubMed:27807006). Important for cell migration, and for normal structure and assembly of the Golgi complex (PubMed:27807006). Important for KDR/VEGFR2 signaling. Increases the stability of KDR/VEGFR2 and prevents its breakdown. Required for normal cardiovascular development. Required for normal angiogenesis, vasculogenesis and hematopoiesis during embryonic development ().